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    Home > Popular Keywords > Keyword List D > dengue serotypes

    dengue serotypes

    Browse diverse articles and stories on dengue serotypes. The information of dengue serotypes is constantly complemented and updated on echemi.com.

    • Nature's hope of curing dengue is rekindled—a pan-serotype dengue inhibitor targeting NS3-NS5 interaction
      Time of Update: 2021-11-04
      Announced that an inhibitor named JNJ-A07 can inhibit 21 dengue virus clinical strains of 4 serotypes at nanomolar to picomolar concentrations; this molecule is not easy to produce drug-resistant mutations, and targets the blocking viruses NS3 and NS4B To prevent the formation of viral replication complexes; mouse experiments show that it has excellent pharmacokinetic characteristics and good safety, can play a preventive effect, and is also effective when delayed administration .
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