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binding primary

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Two different point mutations in ABL gene ATP-binding domain conferring primary imatinib resistance in a chronic myeloid leukemia (CML) patient: A case report

 Time of Update: 2021-03-07

Detection of mutations is helpful in clinical management of imatinib resistance. We established a very sensitive (ASO)PCR to detect mutations in an imatinib-resistant CML patient. Moreover, this ASO-PCR assay is very effective in detecting mutations related to imatinib resistance.

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