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    types transport mechanism cell

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    • Dev Cell | Sheng Zuhang's team reveals the neurodegenerative pathogenic mechanism of nerve cell
      Time of Update: 2021-04-23
      This study found a new pathological mechanism of NPC in the nervous system: excessive accumulation of cholesterol on the surface of the lysosome membrane caused abnormal non-functional recruitment of the transport motor protein Kinesin-1 and mediator protein Arl8, thereby reducing the lysosome from the cell body to the axis The transport efficiency of the distal end of the axon causes the loss of autophagy clearance in the axon and leads to the degeneration of the neuron axon.
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