100000 genome project: 10 pharmaceutical companies work together to build the world's largest gene pool!

Source: bioprospecting March 27, 2015 British time March 26, according to reports from fierecebiotech, the financial times, gene and other websites, a large number of world leading pharmaceutical giants are sequencing the genome of 100000 people to the UK When the project hit, these pharmaceutical companies aimed to find new ways to treat cancer and rare diseases by mining genetic data Ten pharmaceutical companies, including GlaxoSmithKline, AstraZeneca and Roche Pharma in Switzerland, are included in the list of gene consortium They will work together with NHS to file the gene sequence of 100000 patients by 2017 and build the world's largest gene database Genomics England, which is mainly responsible for the "100000 person genome sequencing" project, is a state-owned enterprise in the UK Recently, it has completed the construction of gene library sequences of 3000 cancer or rare disease patients in the trial operation stage, and will complete a total of 10 by 2017 The construction of gene sequence library of 10000 patients aims to develop more accurate individual medical methods by using gene database In 2014, the company also mined many elite data analysts from various industries to analyze the measured genome data, and hoped to develop a safe, effective and replicable model (program) John Chisholm, executive chairman of genomics England, said that the program needs industry cooperation to benefit more patients, but he also stressed that the construction of gene sequence library and the use of gene database in the future will be strictly controlled to ensure the anonymity and non outflow of patient data The UK government last year launched a similar program called care Data, which wanted to provide patient information for research institutions to develop new treatment methods, but at that time was strongly opposed by privacy groups and forced to delay Chisholm said the 100000 patients who received the construction of gene sequence library were all volunteers, which relatively reduced the controversy of privacy Chisholm has many years of experience in the software engineering industry and led the privatization of Qinetiq, a British defense technology enterprise "Most of my career has been devoted to the microelectronics revolution," he said That revolution changed the 20th century, and now genetics will change the 21st century " At present, John Chisholm is mining genetic data of NHS patients, and has combined more than 4000 researchers and experts from some private institutions in the UK The list of 10 pharmaceutical companies shortlisted this time is known as "gene Consortium", which is known as its enterprise consortium The group includes GSK, Roche, AstraZeneca, Baijian, Alberta, UCB, alexion, Takeda, heliomics and dimension therapeutics Companies 23andMe, invested by Google, also launched the construction plan of gene database, and sold a $99 DNA testing tool group However, the company only sequenced part of human genes, unlike genomics England, which archives the complete gene sequence of each patient, so it is expected that the database scale of the latter will be considerable And genomics England said that they are in the upper reaches of the gene industry ecosystem, and this cooperation with large pharmaceutical companies will expand the benefits of this project London cardon, senior vice president of GSK, said that as one of the first 10 enterprises to be shortlisted, it is a great honor to join the project of genomics England, because it is a win-win cooperation opportunity for both parties, whether it is for future drug development or short-term R & D Cardon also said in an external statement that genomics England's program gives us the opportunity to use genomic information to understand the origin of human diseases This allows us to grasp the target more accurately when developing drugs, which we believe will improve our success rate in new drug development Global gene industry trend: there is no doubt that the UK government's cooperation in genome research is becoming the global trend of the industry This week Amgen's decode gene released the genome sequence of tens of thousands of Icelandic samples, and regeneron ($regn) is working on a similar project At the beginning of the year, Barack Obama also proposed the plan of precision medicine, and the United States will invest 215 million dollars to sequence the American genome At the same time, the Chinese government is also following the trend Professor Wang Yongjun, vice president of Stroke Society of China and vice president of Beijing Tiantan Hospital, revealed at the first academic annual meeting of Stroke Society of China and international Cerebrovascular Disease Conference of Tiantan that on March 11, the Ministry of science and technology held the first national strategic expert meeting of precision medicine and proposed that China's precision medicine plan would be launched in the second half of 2015 or next year " By 2030, China's precision medicine will invest 60 billion yuan, including 20 billion yuan from the central government and 40 billion yuan from enterprises and local governments