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On March 30, ImmuneOncia Therapeutics and 3D Medicines signed an exclusive license agreement for the anti-CD47 monoclonal antibody IMC-002.
According to the terms of the agreement, ImmuneOncia will receive an advance payment of US$8 million from Sidi Medicine.
IMC-002 is a fully human IgG4 monoclonal antibody designed to block the CD47-SIRPα interaction to promote the phagocytosis of cancer cells by macrophages.
Prior to this, in September last year, AbbVie received nearly US$2 billion in CD47 antibody development rights from Tianjing Biosciences; in March last year, Gilead purchased US$4.
▲The mechanism of action of anti-CD47 antibody (picture source: "Nature Biomedical Engineering")
Reference materials:
[1] ImmuneOncia and 3D Medicines Signed Exclusive License Agreement to Develop, Manufacture and Commercialize IMC-002 in Greater China.