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A brief analysis of the development status of domestic linear accelerator and gamma knife subdivision

 Last Update: 2022-10-25
 Source: Internet
 Author: User

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Radiation therapy (hereinafter referred to as radiotherapy) is the main treatment for
cancer.
At present, the penetration rate of radiotherapy in China is still low, mainly due to the lack of
radiotherapy equipment.

Radiotherapy equipment mainly includes medical linear accelerator, gamma knife (also known as cobalt 60 treatment machine), Cyberknife, spiral tomotherapy system, proton heavy ion equipment, etc
.
Among them, medical linear accelerator and gamma knife are two types of radiotherapy equipment with a large number of domestic products, and they are also two subdivisions with
extensive clinical applications.

The localization process of medical linear accelerators needs to be accelerated

Medical linear accelerator uses microwave electric field to accelerate electrons to produce high-energy rays, which has the characteristics of large dose rate, short irradiation time, large irradiation field, dose uniformity and stability, and is widely used in the treatment
of primary or secondary tumors in multiple parts of the body.

According to the different acceleration capabilities, medical linear accelerators can be divided into low-energy machines and high-energy machines
.
Among them, the low-energy machine is mainly suitable for the treatment of deep tumors; The high-energy machine has a wider range of applications, covering deep tumors and superficial tumors
.

Researchers from the National Cancer Center, the National Cancer Clinical Research Center and other institutions published in the journal "2019 Chinese mainland Radiotherapy Personnel and Equipment Basic Survey Research" show that in 2018, the number of radiotherapy equipment (including medical linear accelerators) per million people in China was 1.
5, lower than the requirements of the World Health Organization (WHO) (2~4 units), and lower than the level of developed countries and regions (6~12 units).

The low penetration rate of radiotherapy equipment such as medical linear accelerators in China is mainly due to the slow progress of related product research and development, especially the technical barriers of high-end product research and development still need to be broken
.
At present, domestic medical linear accelerator R & D and production enterprises mainly include Xinhua Medical, United Imaging Medical, Elekta, etc
.
In terms of research and development, local enterprises are mainly concentrated in the field of low-energy machines, while the high-energy machine market is mainly dominated
by foreign-funded enterprises.
The gap between the R&D and innovation capabilities of local medical linear accelerator enterprises and foreign-funded enterprises is still large, and some core components (such as magnetrons, etc.
) mainly rely on imports
.

Medical Device Data Cloud learned from querying the disclosed brand data that in 2021, in China's medical linear accelerator market, Varian's market share was as high as 47.
44%, ranking first; The market shares of Elekta and Accuray are 40.
99% and 7.
77% respectively, ranking second and third
respectively.
Local companies United Imaging Healthcare and Xinhua Medical ranked fourth and fifth respectively, with a combined market share of about 3.
3%.

Gamma knife domestic brands have a high market share

Gamma knife is usually composed of cobalt-60 radioactive source, source container, protective handpiece, collimator, treatment bed, control system, etc.
, mainly used for stereotactic radiotherapy (SRT) and stereotactic body radiotherapy (SBRT), which has the advantages
of high precision, safety and reliability, high degree of automation, and less side effects.
In recent years, with the development of precision medicine, the market demand for gamma knife has gradually been released
.

In China, unlike the medical linear accelerator market dominated by foreign brands, Gamma Knife is in the field of radiotherapy equipment, one of the subdivisions with the smallest gap between China's research and development technology and the international level, and the market share of domestic brands is relatively high
.

At present, domestic enterprises that have obtained the Gamma Knife product registration certificate mainly include Masip, Aowo Medical, Haibo Technology, etc
.
Masip's 2020 financial report shows that the market share of the company's gamma knife products has exceeded 50%, ranking first in the country, and the global installed capacity has exceeded 110 units
.
In addition, Aowo Medical is also one of the representative enterprises of Gamma Knife in China, which independently developed China's first Gamma Knife
in 1995.

On the whole, the penetration rate of radiotherapy equipment in China still has a lot of room for
improvement.
For domestic enterprises, the core technical barriers of high-end radiotherapy equipment need to be broken through, and the road of import substitution is still a long
way off.
(Author: Zhongcheng Medical Equipment Research Institute)

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