A kind of OTC drug - thiooctanoic acid has the therapeutic effect of improving patients' life span

For malignant secondary multiple sclerosis patients, the current treatment is very limited However, a recent pioneering study by researchers from ohsh has shown that a class of OTC drugs (http:// - thiooctanoic acid can improve the life of patients The results were published in the latest issue of neuroinformatics & neuroinformation The double-blind study involved 51 participants, 27 of whom received 1200 mg of lipoic acid a day, while the rest received a placebo "The dosage of this drug is indeed high," said Rebecca Spain, the first author of the article and assistant professor from ohsh medical school "Although the research results show that this dose of lipoic acid is within the safe range, whether this dose has therapeutic effect needs further and larger sample size research." Multiple sclerosis is a common chronic disease, which affects the health of 2.3 million people around the world (http:// For multiple sclerosis patients, the outer sheath of brain and spinal nerve fibers is damaged, so the efficiency of brain signal transmission to peripheral organs is significantly reduced The main breakthrough of this study is to detect brain atrophy by MRI technology (http:// and accurately refine the therapeutic effect of lipoic acid The results showed that compared with the control group, the rate of brain atrophy in the patients taking the drug could be reduced by 68% However, ocrevus, which is approved by FDA (http:// for the treatment of multiple sclerosis, has only 18% effect of slowing down the rate of brain atrophy In addition, the study found that patients taking lipoic acid had a significant increase in walking time per day and a decrease in the risk of death The researchers believe that this result needs to be confirmed by a larger scale of research.