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Even mild cases of COVID can have significant and long-term effects on people's health, and one of the key findings of a multinational study on Long Covid (hereinafter referred to as "Long Covid") was recently published in the Journal of
the American Medical Association.
Long crown refers to the persistence or development
of symptoms three months after SARS-CoV-2 (the virus that causes new coronary pneumonia) first infection.
These symptoms persist for at least two months after onset with no other explanation
.
We found that, shockingly, 90% of people infected with long crown infection initially had only mild COVID
.
However, after developing a long crown, the typical person develops symptoms
that affect daily functioning, including fatigue, shortness of breath, and cognitive problems such as brain fog.
The health effects of these symptoms are as severe
as the long-term effects of traumatic brain injury.
Our study also found that women are twice as likely to develop long crowns as men and four times
more likely to have children.
We analysed data from 54 studies that reported more than 1 million people from 22 countries who experienced symptoms
of COVID.
We counted how many people with COVID developed new symptoms and determined how their risk changed
based on their age, gender, and whether they were hospitalized for COVID.
We found that people hospitalized for COVID were at greater risk of developing coronary compared to those who were not hospitalized
.
However, because the vast majority of COVID cases do not require hospitalization, more long-COVID cases have emerged in these milder cases
, despite the lower risk.
Of all those with long crowns, our study found that nearly one in seven still have these symptoms a year later, and researchers don't yet know how many of these cases could become chronic
.
Why it matters
Compared to COVID, we know relatively little
about long crowns.
Our systematic, multi-country analysis of the situation illustrates the enormous human and economic costs
that a long global crown can cause.
Many people with this disorder are working-age adults
.
Months of not being able to work can cause people to lose their income, livelihood and housing, and this situation may also prevent them from caring for their loved ones
.
Long crowns can affect almost any organ of the body
We believe that based on the prevalence and severity of the long crown, it makes it impossible for people to work, which leads to labor shortages
.
Long crowns can also be a factor
that disproportionately affects women when people lose their jobs.
We believe that finding effective and affordable treatments for people with long crowns should be a priority
for researchers and research funders.
COVID clinics have long offered specialized care, but the treatments they offer are limited, inconsistent, and potentially costly
.
What to do next
Long crown is a complex and dynamic disease in which some symptoms disappear and then recur with new symptoms
.
But researchers don't yet know why
.
While our research focused on the three most common symptoms associated with long crowns that affect daily functioning, the condition may also include symptoms
such as loss of smell and taste, insomnia, gastrointestinal problems, and headaches.
But in most cases, these additional symptoms come
along with the primary symptoms we estimate.
There are many unanswered questions
about what causes people to grow crowns.
For example, how do different risk factors, including smoking and high body mass index, affect people's likelihood of developing the disease? Does reinfection with SARS-CoV-2 change the risk of long crowns? In addition, it is unclear what
will happen over time after receiving the COVID vaccine or booster vaccine.
The coronavirus variant also poses new challenges
.
Researchers know that the Omicron variant is more deadly
than previous strains.
Preliminary evidence suggests that Omicron has a lower risk of infection with the long crown compared to earlier strains, but more data
are needed.
Most of the people we studied were infected with deadly variants that were circulating before Omicron became dominant
.
As part of the Global Burden of Disease Study, we will continue to strengthen our research on Chang Corona, which estimates deaths and disabilities from a variety of diseases and injuries in countries around the world to gain a clearer picture of how long-term COVID-19 deaths change once COVID arrives
.