A new oral insulin capsule developed by US researchers

A new oral insulin capsule developed by US researchers is expected to replace subcutaneous injection for daily use in patients with type 2 diabetes in the future The capsule is about the size of a blueberry and contains a small needle that "injects" the drug (http:// into a blood vessel under the stomach wall, according to a study published in the US journal Science Animal experiments showed that its hypoglycemic effect was similar to that of subcutaneous injection The needle consists of a pure lyophilized insulin needle tip and a biodegradable needle rod, which is fixed on a compression spring wrapped in sugar When the water in the stomach dissolves the sugar, the spring will be released, the tip of the needle will be inserted into the stomach wall without pain nerve, and it will be completely released into the blood after about an hour, while the injection under the stomach wall avoids the degradation of insulin by acid gastric juice The spring and other parts of the capsule can finally be discharged through the digestive system The researchers also learned from the cheetah turtle's ability to "reset itself." The tortoise from Africa has a tall tortoise shell that can be recovered after being turned over The researchers designed the shape of the capsule so that it can adjust its position in the stomach to ensure that the tip of the needle can always be successfully inserted into the stomach wall The researchers' experiments on pigs showed that the capsule delivered 300 micrograms of insulin successfully, and then increased the dose to 5 milligrams, which is equivalent to the amount of insulin required by patients with type 2 diabetes In the future, the researchers say, patients are expected to have easier ways to take their medicine, especially for those who need an injection Next, the researchers will continue to conduct animal experiments and try to conduct human experiments on the capsule (http://