A summary of key processing technology advantages of Ketuo's probiotics (lactic acid bacteria)

In the application of probiotics industry, the key processing technology of probiotics is one of the important cores in the industry . Probiotic products produced by high-quality probiotic companies must not only ensure the selection of strains with clear sources and clear probiotic effects, but the quality of their key processing technologies is also a key factor affecting the quality of probiotic products. How to ferment to ensure strain activity? Improving product stability and how to choose product packaging are all topics worthy of everyone's attention . As a leading company in the probiotics industry in China, Ketuo Biotech attaches great importance to the breakthrough of probiotics (lactic acid bacteria) production and processing technology. Let's introduce them one by one! Advantage 1: Preservation and screening of strain resources The preservation and screening of strain resources has always been the core of the probiotic industry. Ketuo Biosciences has established the largest strain resource bank in Asia in cooperation with universities and scientific research institutes. 21268 strains are deposited . After years of scientific research and strain screening, Ketuo currently has more than 120 industrialized strains . Stability is the key to the selection of industrialized strains. For this reason, on the one hand, the R&D personnel of Ketuo Biosciences established a seed batch system in accordance with the medical grade standards to ensure the stability of thousands of generations; on the other hand, the physiological control of each batch of seeds Biochemical, genetic and other aspects of testing to ensure its safety . 　　Advantage 2: Fermentation culture and process control 　　For fermentation culture and process control, Ketuo Biotech first conducts a comprehensive evaluation of the strains, including their physical, chemical and metabolic characteristics; secondly, determines the fermentation equipment according to the characteristics of the strains, and controls them in accordance with GMP requirements. a plurality of detection processes 600, i. e. , including the production environment, the production of raw materials, intermediates fungus powder was measured .   　　Advantage 3: Low-temperature freeze-vacuum drying technology 　　probiotics (lactic acid bacteria) are less tolerated than other types of microorganisms. In order to maintain their high activity at room temperature, freeze-drying technology is involved in the preservation process . The R&D personnel of Ketuo Biotechnology have broken through four key technologies. The first is cell freezing ice crystal damage protection technology to prevent physical damage; the second is cytosolic degeneration protection technology to prevent protein denaturation during solute concentration; third It is the protection technology of molecular covalent supplementation activity; the fourth is the protection technology of oxidation and enzymatic reaction . 　　Advantage 4: Activity control during processing, storage and transportation The processing, storage and transportation process of 　　probiotic products is also very critical, which will directly affect its shelf life . For this reason, Ketuo Biotechnology has monitored the key points that affect bacterial activity such as water activity, oxygen and temperature; in addition, in the selection of packaging materials, Ketuo Biotechnology selects special aluminum film as the packaging of probiotic products to maintain a relatively high Long shelf life .   　　Advantage 5: Smart strain processing plant In 　　2018, Ketuo Biotech invested 150 million yuan to build a GMP-compliant smart strain processing plant, which can produce 200 tons of lactic acid bacteria powder and 200 tons of other products per year . The establishment of a smart strain factory can achieve traceability management of the probiotic production process and strengthen corporate quality management; it has more than 5,000 automated control points for real-time data analysis to ensure the stability of probiotic products .   　　As the so-called good probiotic products not only have good strains, they also need high-quality high-activity processing technology and intelligent strain processing plants to produce good probiotic products, and Ketuo Biosciences is the industry leader in these aspects. Status . Ketuo Biotech always regards science and technology as its primary productivity, and adheres to scientific evidence-based. Currently, it has carried out more than 50 clinical trials in more than ten domestic tertiary hospitals, published more than 300 academic papers, and applied for more than 100 invention patents. . 　　In the future, Ketuo will continue to increase the exploration of advanced probiotics processing technology, including research on new formulations, refined processing of epibiotics, etc. , and strive to create new technological breakthroughs to help the new development of the probiotic industry!   Disclaimer: This article only represents the author's personal views and has nothing to do with China Probiotics. com . The originality and the text and content stated in the article have not been verified by this site. This site does not make any guarantee or promise for the authenticity, completeness, and timeliness of this article, all or part of the content, and the text. Readers are invited for reference only, and please Verify the relevant content yourself .   Copyright Notice 1. Some of the articles reproduced on this site are not original, and the copyright and responsibilities belong to the original author . 2. All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and clearly indicate the source and author. Media or individuals who do not want to be reprinted can contact us for infringement information that can provide sufficient evidence , Bio149 will be deleted within 12 hours after confirmation . 3. Users are welcome to post original articles to 86371366@qq. com, and publish them to the homepage after review. The copyright and liability belong to the sender .

　　In the application of probiotics industry, the key processing technology of probiotics is one of the important cores in the industry
.
Probiotic products produced by high-quality probiotic companies must not only ensure the selection of strains with clear sources and clear probiotic effects, but the quality of their key processing technologies is also a key factor affecting the quality of probiotic products.
How to ferment to ensure strain activity? Improving product stability and how to choose product packaging are all topics worthy of everyone's attention
.
As a leading company in the probiotics industry in China, Ketuo Biotech attaches great importance to the breakthrough of probiotics (lactic acid bacteria) production and processing technology.
Let's introduce them one by one!

　　Advantage 1: Preservation and screening of strain resources The preservation and screening of

　　strain resources has always been the core of the probiotic industry.
Ketuo Biosciences has established the largest strain resource bank in Asia in cooperation with universities and scientific research institutes.
21268 strains are deposited
.
After years of scientific research and strain screening, Ketuo currently has more than 120 industrialized strains
.
Stability is the key to the selection of industrialized strains.
For this reason, on the one hand, the R&D personnel of Ketuo Biosciences established a seed batch system in accordance with the medical grade standards to ensure the stability of thousands of generations; on the other hand, the physiological control of each batch of seeds Biochemical, genetic and other aspects of testing to ensure its safety
.


　　Advantage 2: Fermentation culture and process control

　　For fermentation culture and process control, Ketuo Biotech first conducts a comprehensive evaluation of the strains, including their physical, chemical and metabolic characteristics; secondly, determines the fermentation equipment according to the characteristics of the strains, and controls them in accordance with GMP requirements.
a plurality of detection processes 600, i.
e.
, including the production environment, the production of raw materials, intermediates fungus powder was measured
.

　　Advantage 3: Low-temperature freeze-vacuum drying technology

　　probiotics (lactic acid bacteria) are less tolerated than other types of microorganisms.
In order to maintain their high activity at room temperature, freeze-drying technology is involved in the preservation process
.
The R&D personnel of Ketuo Biotechnology have broken through four key technologies.
The first is cell freezing ice crystal damage protection technology to prevent physical damage; the second is cytosolic degeneration protection technology to prevent protein denaturation during solute concentration; third It is the protection technology of molecular covalent supplementation activity; the fourth is the protection technology of oxidation and enzymatic reaction
.


　　Advantage 4: Activity control during processing, storage and transportation
The processing, storage and transportation process of

　　probiotic products is also very critical, which will directly affect its shelf life
.
For this reason, Ketuo Biotechnology has monitored the key points that affect bacterial activity such as water activity, oxygen and temperature; in addition, in the selection of packaging materials, Ketuo Biotechnology selects special aluminum film as the packaging of probiotic products to maintain a relatively high Long shelf life
.
　　Advantage 5: Smart strain processing plant In

　　2018, Ketuo Biotech invested 150 million yuan to build a GMP-compliant smart strain processing plant, which can produce 200 tons of lactic acid bacteria powder and 200 tons of other products per year
.
The establishment of a smart strain factory can achieve traceability management of the probiotic production process and strengthen corporate quality management; it has more than 5,000 automated control points for real-time data analysis to ensure the stability of probiotic products
.
　　As the so-called good probiotic products not only have good strains, they also need high-quality high-activity processing technology and intelligent strain processing plants to produce good probiotic products, and Ketuo Biosciences is the industry leader in these aspects.
Status
.
Ketuo Biotech always regards science and technology as its primary productivity, and adheres to scientific evidence-based.
Currently, it has carried out more than 50 clinical trials in more than ten domestic tertiary hospitals, published more than 300 academic papers, and applied for more than 100 invention patents.

.


　　In the future, Ketuo will continue to increase the exploration of advanced probiotics processing technology, including research on new formulations, refined processing of epibiotics, etc.
, and strive to create new technological breakthroughs to help the new development of the probiotic industry!

---

　　In the application of probiotics industry, the key processing technology of probiotics is one of the important cores in the industry
.
Probiotic products produced by high-quality probiotic companies must not only ensure the selection of strains with clear sources and clear probiotic effects, but the quality of their key processing technologies is also a key factor affecting the quality of probiotic products.
How to ferment to ensure strain activity? Improving product stability and how to choose product packaging are all topics worthy of everyone's attention
.
As a leading company in the probiotics industry in China, Ketuo Biotech attaches great importance to the breakthrough of probiotics (lactic acid bacteria) production and processing technology.
Let's introduce them one by one!

　　Advantage 1: Preservation and screening of strain resources The preservation and screening of

　　strain resources has always been the core of the probiotic industry.
Ketuo Biosciences has established the largest strain resource bank in Asia in cooperation with universities and scientific research institutes.
21268 strains are deposited
.
After years of scientific research and strain screening, Ketuo currently has more than 120 industrialized strains
.
Stability is the key to the selection of industrialized strains.
For this reason, on the one hand, the R&D personnel of Ketuo Biosciences established a seed batch system in accordance with the medical grade standards to ensure the stability of thousands of generations; on the other hand, the physiological control of each batch of seeds Biochemical, genetic and other aspects of testing to ensure its safety
.


　　Advantage 2: Fermentation culture and process control

　　For fermentation culture and process control, Ketuo Biotech first conducts a comprehensive evaluation of the strains, including their physical, chemical and metabolic characteristics; secondly, determines the fermentation equipment according to the characteristics of the strains, and controls them in accordance with GMP requirements.
a plurality of detection processes 600, i.
e.
, including the production environment, the production of raw materials, intermediates fungus powder was measured
.

　　Advantage 3: Low-temperature freeze-vacuum drying technology

　　probiotics (lactic acid bacteria) are less tolerated than other types of microorganisms.
In order to maintain their high activity at room temperature, freeze-drying technology is involved in the preservation process
.
The R&D personnel of Ketuo Biotechnology have broken through four key technologies.
The first is cell freezing ice crystal damage protection technology to prevent physical damage; the second is cytosolic degeneration protection technology to prevent protein denaturation during solute concentration; third It is the protection technology of molecular covalent supplementation activity; the fourth is the protection technology of oxidation and enzymatic reaction
.


　　Advantage 4: Activity control during processing, storage and transportation
The processing, storage and transportation process of

　　probiotic products is also very critical, which will directly affect its shelf life
.
For this reason, Ketuo Biotechnology has monitored the key points that affect bacterial activity such as water activity, oxygen and temperature; in addition, in the selection of packaging materials, Ketuo Biotechnology selects special aluminum film as the packaging of probiotic products to maintain a relatively high Long shelf life
.
　　Advantage 5: Smart strain processing plant In

　　2018, Ketuo Biotech invested 150 million yuan to build a GMP-compliant smart strain processing plant, which can produce 200 tons of lactic acid bacteria powder and 200 tons of other products per year
.
The establishment of a smart strain factory can achieve traceability management of the probiotic production process and strengthen corporate quality management; it has more than 5,000 automated control points for real-time data analysis to ensure the stability of probiotic products
.
　　As the so-called good probiotic products not only have good strains, they also need high-quality high-activity processing technology and intelligent strain processing plants to produce good probiotic products, and Ketuo Biosciences is the industry leader in these aspects.
Status
.
Ketuo Biotech always regards science and technology as its primary productivity, and adheres to scientific evidence-based.
Currently, it has carried out more than 50 clinical trials in more than ten domestic tertiary hospitals, published more than 300 academic papers, and applied for more than 100 invention patents.

.


　　In the future, Ketuo will continue to increase the exploration of advanced probiotics processing technology, including research on new formulations, refined processing of epibiotics, etc.
, and strive to create new technological breakthroughs to help the new development of the probiotic industry!

---

---