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    Home > Biochemistry News > Microbiology News > Academician Xu Jianguo: The new coronavirus refreshes our understanding of SARS and other viruses

    Academician Xu Jianguo: The new coronavirus refreshes our understanding of SARS and other viruses

    • Last Update: 2021-04-24
    • Source: Internet
    • Author: User
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    Recently, Xu Jianguo, academician of the Chinese Academy of Engineering, gave a keynote report on the new crown virus at the 2021 National Elimination Conference.

    He introduced that the new coronavirus is different from the previous coronaviruses, such as SARS virus and MERS virus.
    It spreads quickly and has a wide range.
    Its epidemiological characteristics are similar to those of influenza viruses.
    It has updated many previous understandings of infectious diseases.

    In his keynote speech entitled "New Understanding of the New Coronavirus: Trends and Challenges", Xu Jianguo analyzed the epidemiological characteristics of the new coronavirus and the status of asymptomatic infections.

    He pointed out that the new coronavirus has updated a lot of our understanding of infectious diseases in the past.
    It is different from the previous coronaviruses and has the epidemiological characteristics of influenza viruses.

    For example, the spread of the new coronavirus is widespread.

    The SARS virus was prevalent in 29 countries and regions, and the MERS virus was prevalent in 27 countries and regions.

    According to previous data, there are 220 countries and regions where the new crown is prevalent, which is similar to influenza virus.
    In 2009, influenza A was prevalent in 214 countries and regions.

    In addition, the spread of the new coronavirus is very fast.
    According to research in the United States, the SARS virus, the MERS virus and the new coronavirus are not in the same order of magnitude.

    In 8 months, the global incidence of SARS was 8096, and the global incidence of MERS was only 203 in 12 months.

    According to information on the WHO's official website, as of April 3, a total of 129,902,402 cases of new crowns have been reported worldwide.

    how so? Xu Jianguo's analysis is related to the range of cells that can be infected by the new crown, the speed of virus replication, and the proportion of asymptomatic infections.

    From a virological point of view, the new coronavirus infects more cells than ordinary coronaviruses.
    The SARS virus does not infect goblet and rod-shaped cells.
    The new coronavirus can infect cilia, goblet and rod-shaped cells. Asymptomatic infections have been regarded as the "Achilles heel" of the new crown epidemic prevention and control.

    He said that in infectious diseases, it is very common for people who do not have the disease but are infectious to carry the virus, such as typhoid Mary.

    However, the proportion of asymptomatic infections of the new crown is very high, higher than that of MERS and SARS.

    The proportion of asymptomatic infections of the new crown in different regions ranged from 6.
    3% to 96%.

    For some domestic epidemics, the early detections were not patients but asymptomatic infections, such as the Kashgar epidemic in Xinjiang.

    The main scenarios for asymptomatic infected persons to spread the virus include confined spaces such as gatherings, banquets, riding in cars, elevators, shopping, meetings, and training.

    He believes that detecting and controlling asymptomatic infections is a very important part of controlling the epidemic.

    In addition, early reports from Wuhan found that the spread of the virus had already begun before the new crown patients developed symptoms.

    Some literature reports pointed out that the time to peak viral load in nasopharyngeal swabs of patients with new crown is shorter than that of SARS virus.

    SARS is mountain-shaped.
    From the onset of symptoms to the peak of the viral load, there is a "climbing" process.

    Before the onset of symptoms, the viral load of nasopharyngeal swabs has reached its peak, and the risk of infection is very high.

    Some researchers inoculated the virus into the cells to observe its replication speed.

    The SARS virus reaches its peak in 72-96 hours, the new coronavirus only takes 48-72 hours, and the influenza virus takes 24 hours.

    The new coronavirus on the surface of nasal mucus and sputum can survive 36 hours and 48 hours at a relative humidity of 40%, 4°C and 21°C.

    In addition, the new coronavirus has a strong ability to survive in the environment.
    It is more stable on the surface of cloth, glass, and plastic than influenza virus, and is still infectious after 72 hours; at a relative humidity of 65% and 22°C, it is more stable than influenza virus.
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