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| AI predicts the animals most likely to spread the new coronavirus |
| Mink, pangolin and bats are among the best |
Science and Technology Daily, Beijing, November 22 (Reporter Liu Xia ) Scientists at the Cary Ecosystem Research Institute in New York, USA, have recently developed an artificial intelligence tool to analyze 5,400 mammals to predict which are most likely to spread the new coronavirus
.
The prediction of this model shows that mink, pangolin and bat are in the top 10%, which is in line with the results provided by the laboratory
.
Liu Xia
The researchers explained that the new coronavirus infects humans and animals by binding the ACE2 protein on the host cell to its spike protein
.
However, the ACE2 protein of different species is different, so knowing the degree of binding of its ACE2 protein to the coronavirus spike protein can help predict which animals are most likely to infect and spread the new coronavirus
.
To solve this problem, the latest research has developed a machine learning tool to predict whether the ACE2 protein of 5,400 mammals can bind tightly with the spike protein of the original coronavirus and its mutant strains to spread the virus even if they are not known.
The amino acid sequence of ACE2
.
The research team first estimated the binding strength of the ACE2 protein and spike protein of 142 mammals with known ACE2 sequences, and whether these species may transmit coronaviruses
.
Subsequently, they provided artificial intelligence tools with the heritability of these 142 species and 60 pieces of information related to the ecological and biological characteristics of the species, so that they could identify the relationship between heritability and various characteristics
.
The results show that the model can predict the possibility of 5,400 mammals to transmit the new coronavirus
.
Among them, white-tailed deer (recently discovered that they have a very high probability of being infected with the new crown virus in North America), striped skunks, 76 species of rodents including certain rats and deer, and some farmed species (such as buffalo), etc.
, are all likely to spread New crown virus
