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Alzheimers Dementia: Different tau proteins have inconsistent predictive effects on cognitive ability

 Last Update: 2021-08-27
 Source: Internet
 Author: User

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Neurofibrillary tangles composed of hyperphosphorylated tau in neurons are one of the hallmark pathological features of Alzheimer's disease (AD), in addition to amyloid β (Aβ) plaques and neurodegeneration
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An immunoassay that measures the phosphorylation of threonine 181 in the cerebrospinal fluid (CSF) of tau181 (p-tau181) has been developed as a biomarker of neurofibrillary tangles to support the diagnosis of AD dementia

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