 Home > Active Ingredient News > Antitumor Therapy > Am J Hematol: cfDNA technology to detect MYD88 L265P and CXCR4 S338X mutations in Waldenstrom's macroglobulinemia

Am J Hematol: cfDNA technology to detect MYD88 L265P and CXCR4 S338X mutations in Waldenstrom's macroglobulinemia

 Last Update: 2021-05-08
 Source: Internet
 Author: User

Tags

ru free

cancer cell journal

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

MYD88 and CXCR4 mutations are very common in Waldenstrom's macroglobulinemia (WM) and can affect the disease's performance, prognosis, and/or therapeutic effect.

diagnosis

Researchers prospectively collected matching BM and PB samples from 28 WM patients, and separated a total of 5 different tissue parts for analysis: CD19-enriched BM, unenriched BM, CD19-enriched PB, Unenriched PB, and cfDNA.

The results show that MYD88 and CXCR4 have high sensitivity and specificity in plasma cfDNA of WM patients (including those who have received previous treatment).

In summary, the results of this study indicate that the use of cfDNA represents a non-invasive, convenient and potentially cost-effective method for genotyping WM patients.

Original source:

ncbi.

ncbi.
nlm.
nih.
gov/?term=Demos+MG&cauthor_id=33819355">The Demos G maria ncbi.
nlm.
nih.
gov/33819355/" target="_blank" rel="noopener">the Cell-Free Analysis for Detection of the DNA and of CXCR4 S338X MYD88 L265P mutations in Waldenström macroglobulinemia in this message

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Gefitinib

CAS No.: 184475-35-2

Pharmacy Grade

$1/MT FOB

High quality Sunitinib CAS NO 557795-19-4 Orange solid powder 99% API for antitumor

CAS No.: 557795-19-4

Pharmacy Grade

$4.1-4.2/G FOB

Epirubicin

CAS No.: 56420-45-2

$1/KG EXW

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

announcements today(81)

80 20 company(94)

united states logo(227)

single use technology(195)

healthy food name(42)

ups united states(221)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.