Amplification Refractory Mutation System and Molecular Diagnostics
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Last Update: 2020-12-19
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Source: Internet
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Author: User
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Allele-specific polymerase chain reaction (
PCR
) was first described in 1989, with variations arising over the next few years such as allele-specific oligonucleotide PCR, mutant-allele-specific amplification (MASA), PCR amplification of specific alleles (PASA), and the amplification refractory mutation system (ARMS) (
1
–
5
). For convenience, the term ARMS will be used here when referring to them collectively.
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