Anaesthesia: Vascular inhibitors are given during spinal anesthesia during caesarean section to prevent hypotension.

Caesarean section spinal cord anaesthetic usually causes low blood pressure in the mother.
systematic review and network meta-analysis compared the method of preventing hypotension in women with spinal cord anaesthetic by caesarean section.
by searching FORDLINE and Embase, Web of Science through December 2018, the researchers selected a randomized controlled trial comparing interventions to prevent hypotension with another intervention or ineffective control measure.
no language restrictions.
two reviewers extracted data on the characteristics, methods and results of the experiment.
evaluated the risk of bias (Cochrane tool) and the quality of evidence (GRADE checklist) for individual trials.
the final researchers evaluated 109 trials (8,561 women) and 12 different methods and made 30 direct comparisons.
ordered by OR (95%CI) from the most effective to the most ineffective methods are: methanol 0.11 (0.04-0.26); Vegetarian 0.18 (0.11-0.29); leg compression 0.25 (0.14-0.43); ephedrine 0.28 (0.18-0.43); giving colloids 0. 38 (0.24-0.61); angiocontin 2,0.12 (0.02-0.75); colloidal 0.52 (0.30-0.90) after anaesthetic induction; 0.09 (0.01-1.30), 0.78 (0.46-1.31) after anaesthetic induction, 1.16 (0.76-1.79) before anaesthetic induction.
compared to the control group, epinephrine caused maternal cardiothosis, OR (95%CI) 0.23 (0.07-0.79).
ephedrine lowers the umbilical artery pH than epinephrine, and the standardized average difference (95% CI) is 0.78 (0.47-1.49).
, the results show that healthy women should be given vascular inhibitors to prevent hypotension during the caesarean section of spinal anesthesia.
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