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    Home > Biochemistry News > Microbiology News > Analysis of Linker Histone Binding to Mono- and Dinucleosomes

    Analysis of Linker Histone Binding to Mono- and Dinucleosomes

    • Last Update: 2021-01-24
    • Source: Internet
    • Author: User
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    The assembly of DNA into the eukaryotic nucleus via an ascending hierarchy of intermediate chromatin structures has two major functional consequences:
    1. 
    The intermediate chromatin structures provide a filing system that greatly facilitates the search by RNA polymerase for regulatory DNA and the associated trans-acting factors.
    2. 
    The wrapping of DNA around the histones provides a means of compacting a large mass of DNA containing many genes while retaining specific sequences in an exposed and accessible state.
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