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    Home > Active Ingredient News > Anesthesia Topics > Anesth Analg: Epidural application of ropivacaine to reduce the amplitude of transcranial motor evoked potentials: a double-blind, randomized, controlled trial

    Anesth Analg: Epidural application of ropivacaine to reduce the amplitude of transcranial motor evoked potentials: a double-blind, randomized, controlled trial

    • Last Update: 2021-09-03
    • Source: Internet
    • Author: User
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    background

    background

    Epidural local anesthetics mainly act on the epidural nerve roots and can directly act on the spinal cord through the dura mater
    .


    We hypothesized that epidural administration of ropivacaine would reduce the amplitude of transcranial motor evoked potentials by blocking spinal nerve conduction


    method

    method

    According to the epidural concentration of ropivacaine, 30 adult patients undergoing lung surgery were randomly divided into 3 groups: 0.
    2% group, 0.
    375% group and 0.
    75% group
    .


    The blinding method is implemented as follows: the attending anesthesiologist, the doctor in charge of neurophysiological monitoring and the patient do not know the corresponding group


    result

    result

    The data are expressed as median (interquartile range)
    .


    60 minutes after epidural injection of ropivacaine, the 0.


    in conclusion

    in conclusion

    Compared with the low-dose group, epidural administration of high concentrations of ropivacaine reduced the amplitude of motor evoked potentials and prolonged the onset latency of motor evoked potentials and SSEPs
    .


    High concentrations of ropivacaine can act on the motor pathways through the dura mater


    Original source:

    Original source:

    Kenta Furutani, Toshiyuki Tobita, Hideaki Ishii, et al.


    Epidural Administration of Ropivacaine Reduces the Amplitude of Transcranial Electrical Motor-Evoked Potentials: A Double-Blinded, Randomized, Controlled Trial in this message
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