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    Home > Medical News > Latest Medical News > Announcement of Phase Ib clinical results of sintilimab combined with bevacizumab in the treatment of advanced hepatocellular carcinoma

    Announcement of Phase Ib clinical results of sintilimab combined with bevacizumab in the treatment of advanced hepatocellular carcinoma

    • Last Update: 2022-02-18
    • Source: Internet
    • Author: User
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    Innovent and Eli Lilly jointly announced the final clinical study results and biomarker analysis of Dabosu® (sintilimab injection) in combination with bevacizumab in the treatment of advanced hepatocellular carcinoma (NCT04072679) in Phase Ib (NCT04072679).


    The study is a Phase Ib trial (NCT04072679) evaluating the safety, tolerability and antitumor activity in Chinese patients with locally advanced/metastatic hepatocellular carcinoma who have not or failed systemic therapy.


    In terms of efficacy, the overall objective response rate (ORR) was 34% (17/50), with ORRs of 31% and 38% in the low-dose and high-dose groups, respectively


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