Recently, Professor Liu Runhui’s research team from the School of Materials Science and Engineering of East China University of Science and Technology and Professor Lin Haodong’s team from Shanghai First People’s Hospital have prepared PMMA (polymethyl methacrylate) doped with antimicrobial peptide polymers based on host defense peptide simulation.
The treatment of chronic osteomyelitis usually requires multiple operations and long-term antibiotic intervention, and the risk of recurrence is high, which brings huge pain and economic burden to patients
In this study, it was found that the peptide polymer can be quickly released from inert PMMA, quickly onset, and almost completely released, which overcomes the inherent shortcomings of insufficient release of antibiotic bone cement
In the rabbit chronic osteomyelitis animal model, antibacterial bone cement (PMMA@polymer) compared with blank bone cement (PMMA) achieved effective in vivo treatment.
Related paper information: https://doi.
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.
