Application of deep learning in CT images: The use of convolutional neural networks to automatically detect lung nodules for subsequent management.

The application of deep learning in CT images: automatic detection of pulmonary nodules by convolutional neural network for follow-up management was published by Defu medical press in the Journal of cancer management and research. The contents were summarized as follows: Objective: To compare the computer-aided detection based on 3D convolutional neural network (CNN) Detection (CAD) model and different levels of experience of radiologists in the detection of pulmonary nodules on thin slice CT.patients and methods: a retrospective analysis of 1109 patients who received continuous thin-layer CT follow-up in our hospital.through the supplement of experts, the 3d-cnn pulmonary nodule detection model was retrained, and the reference standard was determined by a consensus group composed of two radiologists.in the test set, the free response receiver operating characteristic (FROC) analysis was performed on the CAD model after retraining and three radiologists with different experience levels to evaluate the detection efficiency.results: the detection efficiency of CAD model after retraining was significantly better than that of the network before training (sensitivity: 93.09% vs 38.44%) and radiologists (average sensitivity: 93.09% vs 50.22%), and there was no significant increase in the false positive number of each scan (1.64 vs 0.68).in the training set, according to the fleischner Association guidelines, 922 nodules less than 3 mm in 211 patients were assessed as high-risk and CT follow-up was recommended.there were 101 solid nodules, 15 of which were diagnosed with lung cancer.conclusion: the CAD model based on 3d-cnn is an accurate and effective tool for pulmonary nodule detection after supplementary retraining by experts, and it also provides a favorable means for subsequent monitoring of pulmonary nodules.key words: computer aided detection; computed tomography; pulmonary nodules; convolutional neural network / / Defu paper video program online! Please scan this QR code! / /