Artemisinin: the mechanism of de-seisting the wax synthesis of plant leaves and the development of glands.

Tang Kexuan research team of Shanghai Jiaotong University's School of Agriculture and Biology made further significant progress in the field of secretion-type adenosic development mechanism represented by artemisinin.
research published online in the journal New Botanists.
many important plant secondary metabolites, including artemisinin and other major production and accumulation in the secretion of gland hairs, secretion-type glands are also known as "plant factories", and the production and accumulation of secondary metabolites in the secretion glands is the production and accumulation of cell region, and thus has an efficient and powerful production capacity, so the study of the initial development of secreted glands is also an important part of synthetic biology and plant development research.
Tang Kexuan team has long studied the development mechanism of plant secretion glands based on artemisinin.
the researchers used the search for a regulatory factor of AaHD1 as the starting point, through yeast monohybrids and Dual-LUC and other methods to find a positive regulation of AaHD1 gene expression of the HD-ZIP IV transcription factor AaHD8.
genetically modified studies found that AaHD8 is regulating artemisinin adenosyhairy development and wax synthesis, further physiological and biochemical analysis found that AaHD8 and AaMIXTA1 can interact to form a complex, by combining AaHD1 and multiple waxhorn artione gene promoters on L1-box, co-regulating the expression of these genes, thereby promoting the initial development of wax synthesis and glandhairation.
experts said that the study took artemisinin as a model plant to further reveal the regulatory network of secretion-type adenhair development, revealed the plant leaf wax synthesis and adenosic hair development of the dissothing mechanism, for the improvement of the secreted gland hair development of the complex regulatory network laid a foundation.
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