Artificial bio-carbon sequestration pathway CETCH cycle technology.

In the November 18 issue of the journal Science, Dr. Gong Fuyu and researcher Li Wei, Ph.D., Key Laboratory of Microbiology and Metabolism Engineering at the Institute of Microbiology of the Chinese Academy of Sciences, published an outlook article entitled "Unnarote carbon sequestration" in the Insights/Perspectives section.
the CETCH cycle of the artificial biosealed carbon sequestration pathway published in the same period in this paper.
rising concentrations of carbon dioxide in the atmosphere, prompting scientists to develop new technologies for carbon dioxide conversion and utilization.
nature itself has the ability to bio-convert and utilize carbon dioxide.
six natural bio-carbon sequestration pathways have been found in aerobic or anaerobic organisms, including the Calvin cycle, which is known to be widely found in plants and algae.
, however, these natural carbon sequestration pathways are characterized by low energy efficiency and slower speeds.
even if these natural carbon sequestration pathways are heterogeneously reconstructed in microorganisms, the rapid biological transformation of carbon dioxide will not be possible because the basic structure of the carbon sequestration pathways has not been changed.
paper reviews the CETCH cycle of artificial biosealed carbon sequestration pathways published at the same time.
CETCH cycle designed and assembled a new carbon sequestration pathway that does not exist in nature, using the most active carbidase to date, bacarpase A carbidase/reductase, as the starting point for the design of the pathway.
Compared to other natural aerobic carbon sequestration pathways, the shortest and most energy efficient CETCH cycle is an important breakthrough in the field of bioseconding, demonstrating the potential to create non-natural carbon sequestration pathways that go beyond nature through the use of natural carbon sequestration elements.
although in vitro experiments have shown that the CETCH cycle can achieve a carbon sequestration rate comparable to that of the Calvin cycle, it should be noted that the export compound of the CETCH cycle is acetaldehyde acid with a lower reduction.
Compared to other natural carbon sequestration pathways that export compounds such as enzyme-based intermediates or acetyl coenzyme A, it may be more difficult to bind the CETCH cycle to a living cell organism.
much progress has been made in recent years in reconstructing or creating bio-carbon sequestration pathways, energy supply, another important factor limiting bio-carbon sequestration efficiency, needs to be given greater attention.
the future, greatly improving the efficiency of the use of light energy by artificial organisms, or realizing the direct use of low-cost electrical energy, will be the focus of competition in the field of bio-carbon sequestration.
recent years, with the support of the National Natural Science Foundation, the Ministry of Science and Technology's "973" program and the key deployment projects of the Chinese Academy of Sciences, Li Wei's task force has focused on the research of carbon dioxide biosynthetic chemicals.
has created a range of engineering strains that convert carbon dioxide into materials such as lactic acid, acetone, isopropyl alcohol, butanol, isoprene, or energy chemicals, significantly improving the photocodychrosis efficiency of blue bacteria and enabling functional reconstruction of part of the Calvin cycle in E. coli.
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