Artificial sweeteners can transform intestinal flora into pathogenic bacteria and cause human diseases

A new study found that ordinary artificial sweeteners may cause previously healthy intestinal bacteria to disease and invade the intestinal wall-eventually causing serious health problems . This study, published in the International Journal of Molecular Sciences, shows for the first time that some of the most widely used artificial sweeteners—saccharin, sucralose, and aspartame—are used for two Pathogenic effects of enteric bacteria Escherichia coli (E. coli) and Enterococcus faecalis (Enterococcus faecalis) . Previous studies have shown that artificial sweeteners can change the number and types of intestinal bacteria, but this new molecular study led by scholars from Anglia Ruskin University (ARU) shows that sweeteners It can also make bacteria pathogenic . Studies have found that these pathogenic bacteria can attach, invade and kill Caco-2 cells on the intestinal wall . As we all know, bacteria such as Enterobacter faecalis can pass through the intestinal wall into the blood and accumulate in the lymph nodes, liver and spleen, leading to a variety of infections including sepsis . This new study found that at a concentration equivalent to two cans of Diet soft drinks, these three artificial sweeteners significantly increased the adhesion of E. coli and Enterobacter faecalis to intestinal Caco-2 cells, and significantly increased The formation of biofilms . 　　Bacteria that grow in biofilms are less sensitive to antimicrobial resistance treatments, and are more likely to secrete toxins and express virulence factors-eventually leading to disease . 　　In addition, except that saccharin has no significant effect on the invasion of E. coli, these three sweeteners can all cause intestinal pathogenic bacteria to invade the Caco-2 cells in the intestinal wall . 　　These signs all indicate that common artificial sweeteners are likely to induce the body’s previously healthy intestinal flora, make it pathological and invade the intestinal wall . 　　In daily life, there are more and more worries about artificial sweeteners . Some studies have shown that sweeteners can affect the gut microbiota . 　　The above-mentioned research shows for the first time that some of the most common sweeteners in food and beverages—saccharin, sucralose and aspartame—can turn normal and “healthy” gut bacteria into pathogenic bacteria . These pathogenic changes include greater formation of biofilms, and increased adhesion and bacterial invasion of human intestinal cells . 　　They analyzed the pathogenic effects of these artificial sweeteners on two types of intestinal flora-Escherichia coli and Enterococcus faecalis . "These changes may cause our own intestinal bacteria to invade and cause intestinal damage, which may be related to infection, sepsis and multiple organ failure . "   Disclaimer: This article only represents the author's personal views and has nothing to do with China Probiotics. com . The originality and the text and content stated in the article have not been verified by this site. This site does not make any guarantee or commitment to the authenticity, completeness, and timeliness of this article, all or part of the content, and the text. Please readers for reference only, and please Verify the relevant content yourself .   Copyright Notice 1. Some of the reprinted articles on this site are not original, and the copyright and liability belong to the original author . 2. All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and clearly indicate the source and author. Media or individuals who do not want to be reprinted can contact us for infringement information that can provide sufficient evidence , Bio149 will be deleted within 12 hours after confirmation . 3. Users are welcome to post original articles to 86371366@qq. com, and publish them to the homepage after review. The copyright and liability belong to the sender .

A new study found that ordinary artificial sweeteners may cause previously healthy intestinal bacteria to disease and invade the intestinal wall-eventually causing serious health problems
.


　　This study, published in the International Journal of Molecular Sciences, shows for the first time that some of the most widely used artificial sweeteners—saccharin, sucralose, and aspartame—are used for two
Pathogenic effects of enteric bacteria Escherichia coli (E.
coli) and Enterococcus faecalis (Enterococcus faecalis)
.


　　Previous studies have shown that artificial sweeteners can change the number and types of intestinal bacteria, but this new molecular study led by scholars from Anglia Ruskin University (ARU) shows that sweeteners It can also make bacteria pathogenic
.
Studies have found that these pathogenic bacteria can attach, invade and kill Caco-2 cells on the intestinal wall
.


　　As we all know, bacteria such as Enterobacter faecalis can pass through the intestinal wall into the blood and accumulate in the lymph nodes, liver and spleen, leading to a variety of infections including sepsis
.


　　This new study found that at a concentration equivalent to two cans of Diet soft drinks, these three artificial sweeteners significantly increased the adhesion of E.
coli and Enterobacter faecalis to intestinal Caco-2 cells, and significantly increased The formation of biofilms
.


　　Bacteria that grow in biofilms are less sensitive to antimicrobial resistance treatments, and are more likely to secrete toxins and express virulence factors-eventually leading to disease
.


　　In addition, except that saccharin has no significant effect on the invasion of E.
coli, these three sweeteners can all cause intestinal pathogenic bacteria to invade the Caco-2 cells in the intestinal wall
.


　　These signs all indicate that common artificial sweeteners are likely to induce the body's previously healthy intestinal flora, make it pathological and invade the intestinal wall
.


　　In daily life, there are also more and more worries about artificial sweeteners
.
Some studies have shown that sweeteners can affect the gut microbiota
.


　　And the above-mentioned research shows for the first time that some of the most common sweeteners in food and beverages-saccharin, sucralose and aspartame-can turn normal and "healthy" gut bacteria into pathogenic bacteria
.
These pathogenic changes include greater formation of biofilms, and increased adhesion and bacterial invasion of human intestinal cells
.


　　They analyzed the pathogenic effects of these artificial sweeteners on two types of intestinal flora-Escherichia coli and Enterococcus faecalis
.
"These changes may cause our own intestinal bacteria to invade and cause intestinal damage, which may be related to infection, sepsis and multiple organ failure
.
"

---

A new study found that ordinary artificial sweeteners may cause previously healthy intestinal bacteria to disease and invade the intestinal wall-eventually causing serious health problems
.


　　This study, published in the International Journal of Molecular Sciences, shows for the first time that some of the most widely used artificial sweeteners—saccharin, sucralose, and aspartame—are used for two
Pathogenic effects of enteric bacteria Escherichia coli (E.
coli) and Enterococcus faecalis (Enterococcus faecalis)
.


　　Previous studies have shown that artificial sweeteners can change the number and types of intestinal bacteria, but this new molecular study led by scholars from Anglia Ruskin University (ARU) shows that sweeteners It can also make bacteria pathogenic
.
Studies have found that these pathogenic bacteria can attach, invade and kill Caco-2 cells on the intestinal wall
.


　　As we all know, bacteria such as Enterobacter faecalis can pass through the intestinal wall into the blood and accumulate in the lymph nodes, liver and spleen, leading to a variety of infections including sepsis
.


　　This new study found that at a concentration equivalent to two cans of Diet soft drinks, these three artificial sweeteners significantly increased the adhesion of E.
coli and Enterobacter faecalis to intestinal Caco-2 cells, and significantly increased The formation of biofilms
.


　　Bacteria that grow in biofilms are less sensitive to antimicrobial resistance treatments, and are more likely to secrete toxins and express virulence factors-eventually leading to disease
.


　　In addition, except that saccharin has no significant effect on the invasion of E.
coli, these three sweeteners can all cause intestinal pathogenic bacteria to invade the Caco-2 cells in the intestinal wall
.


　　These signs all indicate that common artificial sweeteners are likely to induce the body's previously healthy intestinal flora, make it pathological and invade the intestinal wall
.


　　In daily life, there are also more and more worries about artificial sweeteners
.
Some studies have shown that sweeteners can affect the gut microbiota
.


　　And the above-mentioned research shows for the first time that some of the most common sweeteners in food and beverages-saccharin, sucralose and aspartame-can turn normal and "healthy" gut bacteria into pathogenic bacteria
.
These pathogenic changes include greater formation of biofilms, and increased adhesion and bacterial invasion of human intestinal cells
.


　　They analyzed the pathogenic effects of these artificial sweeteners on two types of intestinal flora-Escherichia coli and Enterococcus faecalis
.
"These changes may cause our own intestinal bacteria to invade and cause intestinal damage, which may be related to infection, sepsis and multiple organ failure
.
"

---

---