Baidu intervenes in the development of a new generation of mRNA drugs and vaccines

Baidu intervenes in the development of a new generation of mRNA drugs and vaccines

Baidu is involved in the development of a new generation of mRNA drugs and vaccines Baidu is involved in the development of a new generation of mRNA drugs and vaccines

Using an autonomous biological computing platform, Baidu is involved in the development of a new generation of mRNA drugs and vaccines
.

A few days ago, Baidu signed an agreement with the biopharmaceutical company Sanofi of France.

LinearDesign is a mRNA sequence design optimization algorithm independently developed by Baidu, and it is an important part of Baidu's layout in the field of biological computing
.

The licensing agreement with Sanofi demonstrates Baidu Biocomputing's ability to optimize mRNA vaccines and treatment design plans, and it is helping biocomputing in the field of drug and vaccine research and development

Baidu Group Vice President Wu Tian said that emerging mRNA technology has rapidly promoted the development of vaccines and drugs for infectious diseases such as new coronary pneumonia.
The combination of biocomputing and mRNA technology makes this process faster and more efficient, and may be used for future drug research and development.
Provide new ideas
.

It is understood that LinearDesign is an algorithm specifically for mRNA sequence design launched by Baidu in 2020.
It can be used to improve the stability and immunogenicity of mRNA encoded by spike proteins.
Its effectiveness has been obtained in in vitro and animal experiments.
Initial verification
.

According to another report, the research and development of the LinearDesign algorithm is inspired by the two algorithms that Baidu previously co-developed-LinearFold, the world's fastest RNA secondary structure prediction algorithm, and LinearPartition, the world's fastest RNA base pairing probability prediction algorithm

At present, the technical paper of the non-commercial version of LinearDesign algorithm has been online
.

(Source: Zhao Guangli, China Science News)

Related paper information: https://arxiv.

https://arxiv.
org/abs/2004.
10177