Bone loss linked to obesity, study finds

With the increasing prevalence of obesity worldwide, the association between obesity and periodontitis has attracted academic attention in recent years, and epidemiological data support a positive association between obesity levels and periodontal disease

Oral problems are never a trivial matter

Although there is a clear relationship between obesity and periodontal disease, early mechanistic studies focused on changes in immune function caused by systemic inflammation

Myeloid progenitors are precursors to erythrocytes, platelets, granulocytes, monocytes/macrophages, stem cells, mast cells and osteoclasts

In the new study, the researchers studied two groups of mice, one fed a low-fat diet with 10 percent of their energy from fat and the other fed a high-fat diet with 45 percent of their energy from fat

In addition, the researchers found that the expression of 27 genes related to osteoclastogenesis was significantly elevated in the mice on the high-fat diet