BQS: Hospital prevalence of COVID-19 is a risk factor for death

Background: Compared with the early stages of the pandemic, the mortality rate associated with COVID-19 has improved
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The impact of the hospital prevalence rate of patients with new coronary pneumonia on the mortality rate of new coronary pneumonia has not been well studied

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Methods: We analyzed data on adults diagnosed with SARS-CoV-2 infection admitted to 62 hospitals in multiple state health systems in the past 12 months
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Mortality is evaluated based on patient demographics and clinical risk factors, hospital prevalence of new coronary pneumonia, and admission calendar time period, using a generalized linear mixed model with a random effect of care location

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Results: 38104 patients with new coronary pneumonia were hospitalized.
During their hospitalization, the prevalence of new coronary pneumonia accounted for an average of 16% of the total number of hospitalizations
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From March to April 2020 to January to February 2021, the mortality rate of new coronary pneumonia dropped from 19% to 12% (p<0.

001)

Compared with patients with low prevalence (<10%) of new coronary pneumonia, the relative risk of death from new coronary pneumonia in hospitalized patients with medium and high new coronary pneumonia (the absolute contribution rate to the probability of death is 2% to 3%) increased by 25% respectively And 41% (high prevalence> 25%: adjusted OR (AOR1.

Figure 1 From March 2020 to February 2021, the number of patients in each institution and the hospital prevalence rate of COVID-19

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Figure 1 From March 2020 to February 2021, the number of patients in each institution and the hospital prevalence rate of COVID-19

Figure 2 The average inpatient prevalence and mortality of hospitalized patients infected with COVID-19 from March 2020 to February 2021, by age

Figure 2 The average inpatient prevalence and mortality of hospitalized patients infected with COVID-19 from March 2020 to February 2021, by age

Table: Adjusted ORs (AORs) of hospital mortality of COVID-19 patients admitted from March 2020 to February 2021

Table: Adjusted ORs (AORs) of hospital mortality of COVID-19 patients admitted from March 2020 to February 2021

Figure 3 The characteristics of the increase in the (absolute) percentage increase in the probability of death (average marginal effect) in patients with new coronary pneumonia

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Figure 3 The characteristics of the increase in the (absolute) percentage increase in the probability of death (average marginal effect) in patients with new coronary pneumonia

Although compared with the early stage of the epidemic, the hospital mortality of patients with new coronary pneumonia has dropped significantly, but the high hospital prevalence of new coronary pneumonia is still a common risk factor for mortality from new coronary pneumonia

Fakih MG, Ottenbacher A, Yehia B,et al, COVID-19 hospital prevalence as a risk factor for mortality: an observational study of a multistate cohort of 62 hospitals .

BMJ Qual Saf 2021 Oct 05

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19-COVID Hospital prevalence AS A Risk factor for mortality: AN observational cohort of Multistate A Study of Hospitals 62 is in this message