Caffeine has been found to reduce the risk of rosacea

Rosacea is a common chronic inflammatory skin disease, which can be induced by many factors, such as caffeine, hot drink, sunlight, spicy food, strenuous exercise, hormones and so on Among them, caffeine can reduce vasodilation and immunosuppression, reduce the risk of rosacea, but the calories in coffee may be the potential cause of rosacea The study was based on a cohort study of 82737 women in the 1989 prospective nurse health study II (http://www.chemdrug.com/article/7/) Data on coffee, tea, soda and chocolate intake were collected every four years during a 14 year follow-up period At the end of follow-up, 4945 rosacea cases were confirmed After adjusting for other confounding risk factors, the researchers found that compared with the lowest quintile caffeine intake array, the highest quintile caffeine intake array significantly reduced the risk of rosacea (HR 0.76; 95% CI 0.69-0.84); P < 0.001), that is to say, caffeine intake was negatively correlated with the risk of rosacea; caffeine intake was also negatively correlated with the risk of rosacea (HR 0.77; 95% CI 0.69-0.87); P < 0.001), but there was no significant correlation between caffeine free coffee or other caffeine containing foods (such as tea, soda or chocolate) intake and the risk of rosacea The influence of caffeine on the risk of rosacea is related to many factors Telangiectasia caused by vasomotor dysfunction plays an important role in the pathogenesis of rosacea, especially papule pustular type Caffeine can act on renin - Angiotension - aldosterone system and make blood vessels contract Caffeine can alleviate rosacea symptoms by reducing capillary relaxation Caffeine has antioxidant and immunosuppressive effects, which may reduce the inflammatory response in Rosa Rosa The hormone in human body has been proved to be related to rosacea Caffeine can regulate the hormone levels of adrenaline and glucocorticoid, and improve symptoms This study found that the increased intake of caffeine and caffeinated coffee can significantly reduce the risk of rosacea, so it is not supported to limit the intake of caffeine to prevent rosacea, and it suggests that caffeine may be the protective factor of rosacea.