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Causes of brain dysfunction in patients with Huntington's disease

 Last Update: 2022-10-03
 Source: Internet
 Author: User

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Figure: Differences in FAK activation and neuronal protrusion formation in the brain tissue of normal and Huntington's disease patients

Source: Korea Advanced Institute of Science and Technology (KIST)

Huntington's disease (HD) is an inherited brain disease

It is reported that the research team of the Institute of Brain Science of the Korea Academy of Science and Technology (KIST, President Yoon Seok-jin) found that the activity of the focus adhesion kinase (FAK) protein, which plays an important role in the movement of nerve processes and normal synaptic formation in the brain tissue of HD patients, was significantly reduced

Activated FAK proteins play an important role in brain function because they are essential in nerve cell movement and normal synaptic formation

Phosphatidylinositol 4,5-diphosphate (PIP2) is a phospholipid found in cell membranes that is essential

Dr.

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