Cell announces the world's largest osteoarthritis study

Osteoarthritis is the leading cause of pain and disability worldwide

There is no cure, only pain relief

Some people are treated with painkillers and exercise

Currently, approximately 300 million people worldwide suffer from osteoarthritis

Now, researchers have completed the largest study in the history of the world

155 researchers from 9 different countries participated in this study

Of all the osteoarthritis variants studied, several findings are shared

"We discovered which genes are associated with osteoarthritis

Skogholt is the director of the Jebsen Center for Genetic Epidemiology, a researcher at the Norwegian University of Science and Technology (NTNU) KG, and a key figure in international cooperation

Researchers also found that women and knee joints and other weight-bearing joints have special risk factors

Some drugs are already in use

One more good news

Some drugs targeting related genes are already in use, but for other diseases

"This means that the path to finding drugs to slow osteoarthritis is shorter than other methods

These genes are essential for the development of bone and cartilage tissue

"Now we need to go one step further and include samples from African countries," Skogholt said

Discover the link between pain and osteoarthritis

She said that previous research findings indicate a link between obesity and osteoarthritis, diabetes and osteoarthritis

"Now, for the first time, we have identified genes related to osteoarthritis and pain," Skogholt said
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The pain caused by osteoarthritis can be disabling, and it can also cause disability
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Skogholt said: "We are really happy that we have made tremendous progress in the right direction for this patient group
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Article title

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations