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Recently, the International MetaSUB Alliance (Metro and Urban Biome Metagenomics and Meta-Design Alliance) reported the results of the largest global urban microbial metagenomics research to date
.
The project collected samples from public transportation systems and hospitals in 60 cities around the world, sequenced and analyzed them, and fully annotated all identified microbial species, including thousands of viruses and bacteria that were not in the reference database, and two Kind of archaea
.
Relevant research results are published in Cell magazine under the title A global metagenomic map of urban microbiomes and antimicrobial resistance
.
The corresponding author of the article is Professor Christopher Mason from Weill Connell Medicine, who is also the principal of the International MetaSUB Alliance
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In this study, the researchers collected samples with cotton swabs that did not contain DNA and RNA, and sent the samples and positive and negative controls to the WCM laboratory for analysis
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Most of the sequence analysis and assembly were done on the Extreme Science and Engineering Discovery Environment (XSEDE) supercomputer in Pittsburgh
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The results of this study are based on 4728 samples from six continents, which were collected within 3 years to characterize regional antimicrobial resistance markers
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Based on these data, the researchers successfully mapped the world's first systematic catalog of urban microbial ecosystems
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In addition to the different microbial characteristics of different cities, the analysis also revealed 31 core microbial species, which were found in 97% of the samples
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The researchers identified 4246 known urban microorganisms, but also found that any subsequent sampling may continue to find species that have never been seen before, which highlights the original potential of discovering microbial diversity and biological functions in the urban environment
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This new research is of great significance for detecting outbreaks of known and unknown microbial infections and studying the prevalence of antibiotic-resistant microorganisms in different urban environments.
It also helps to obtain new discoveries about the evolution of microbial life
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Swiss researchers Andre Kahles and Gunnar Rätsch of the MetaSUB Alliance released a global DNA sequence portal (MetaGraph), which indexes all known gene sequences (including MetaSUB data) and maps known or newly discovered gene elements Going to their location on the earth will help discover new microbial interactions and functions
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About the International MetaSUB Alliance The full name of the International MetaSUB Alliance is "The International Metagenomics and Metadesign of Subways and Urban Biomes"
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In 2015, Christopher Mason created the International MetaSUB Alliance, which has now expanded to collect air, water and sewage, and hard surface samples, and is responsible for overseeing projects such as the Global Urban Sampling Day held on June 21 every year
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The Alliance conducted extensive research, including a comprehensive microbiological analysis of the urban surface of Rio de Janeiro and its mosquitoes before, during and after the 2016 Summer Olympics
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Another project was launched in 2020, focusing on investigating the prevalence of new coronaviruses and other coronaviruses in domestic cats.
They also plan to launch a project for the 2021 Tokyo Olympics in Japan
.
Original link: https:// Plate maker: Notes for reprinting on the 11th [Non-original article] The copyright of this article belongs to the author of the article, and personal forwarding and sharing are welcome.
Reprinting is prohibited without permission, the author has all legal rights, and offenders must be investigated
.