Changes in the gut microbiome or are closely related to the occurrence of colorectal cancer

In a recent study published in the international journal Nature Medicine, scientists from Osaka University found that increased levels of organisms in the gut or associated with the occurrence of malignant tumors associated with colorectal cancer, such as mucous endomea and polyps-like adenomas, suggest that these particular markers may help researchers effectively distinguish samples of colorectal cancer patients from healthy samples'We believe that colorectal cancer is not just a genetic disease, but a microbial disease that may provide key clues to diagnosis and cause of the disease in the early stages of colorectal cancer or changes in the gut microbiome,' said Shinichi Yachida, aresearcherColorectal cancer is the third most prevalent cancer in the world and a relatively slow-moving type of cancer, which means that it often takes a long time for a patient to progress to a late-stage fatality state;, researchers analyzed stool samples from more than 600 patients who underwent colonoscopy to assess the characteristics of their gut microbiome and its association with the onset of colorectal cancerThe researchers said the results suggest that colorectal cancer or increased levels of specific factors in the gut microbiome, as well as the presence of cancer-related organisms, and that later researchers will continue to study the link between gut microbiome and tumor characteristics in the body of colorectal cancer patients, which could hopefully help understand the key role that microbiome plays in the occurrence of colorectal canceroriginal origin:Shinichi Yachida, Sayaka Mizutani, Hirotsugu Shiroma, et alMetagenomic and metabolomic safle safle distinct-specificphenotype of the gut microbiota in colorectal cancerNature Medicine, 2019; 25 (6): 968 DOI: 10.1038/s41591-019-0458-7