Chinese veterinary medicine will become the main force of resistance.

the era of prohibitionx4E
following the Announcement No. 194 issued by the Ministry of Agriculture and Rural Affairs on August 8, 2019, on December 26, 2019, the Ministry of Agriculture and Rural Affairs issued Proclamation No. 246, re-emphasizing that from January 1, 2020, the quality standards of feed additives and other varieties for growth-only use will be abolished; It can be said that I do not know how long to talk about the prohibition of resistance finally came.x4E
no longer allow editing of pharmaceutical additives to feed by 2020, meaning that this part of the business will be unsustainable. At the same time, after a period of time after the prohibition of resistance, farmers' livestock morbidity, mortality and the use of therapeutic drugs may be greatly increased, breeding levels will decline in the short term, production costs may rise, the hardware facilities are very high requirements, the industry will be difficult to avoid short-term pain.x4E
challenges, and prohibition offers a little more opportunities. Fast-transitioning enterprises to get a greater dividend, for anti-products ushered in the historical opportunity, those who dare to break through innovation will be in the future.x4E
the comparison of the three alternative anti-resistance schemesx4E
what to replace antibiotics, each practitioner has its own thinking, but there is a basic consensus, one is acidifier, one is vegetable essential oils, spices, and is to use a high concentration of metal ions, such as zinc oxide. Evaluate the three programmes here.x4E
the first option was to replace antibiotics with acidified agents. Acidification agents need to reduce the pH value of the stomach contents to 3.5 or lower in order to efficiently activate the gastric protease to activate the gastric protease, but to achieve such a low pH level to add how many acidators? Gastric digestion is only very primary digestion, nutrient digestion and absorption of 90% is not in the stomach but in the intestine, especially in the small intestine, so only the stomach acidification, but destroyed the intestinal digestion, it is the end of the upside down. The digestion of the small intestine needs to be carried out in a neutral partial-alkali environment, before the addition of so many exogenous acid, eating slugs into the small intestine can immediately become neutral partial alkali? And in order to make acidic meals become alkaline, you have to rely on the bile in the alkaline bile acid to neutralize. Bile is produced by liver metabolism, and the need for bile too much undoubtedly exacerbates the burden on the liver. Therefore, a one-sided increase in acid is not feasible. Also, to protect acid in the stomach to play a role, to the small intestine does not play a role, to the back of the intestine section again acidification role, the need for too complex package process, the current science and technology is not yet available. The second option is to use high concentrations of metal ions instead of antibiotics to suppress pathogenic microorganisms. Zinc oxide and copper preparations commonly used before to have the effect of sterilization, the amount of addition in the feed needs to reach a very high level, which is not a scientific, rational, safe method for weaning piglets, piglets. If antibiotics can be left, these metal ions are more difficult to eliminate, either in excreted feces or into human body tissue. The third alternative is to use vegetable essential oils or spices, including bovine oil, thyme phenol, cinnamon aldehyde. In fact, humans began using these spices long ago to prevent food from behaving, until antibiotics came out, only to find that these things curb the role of microorganisms and antibiotics can not be compared. Antibiotics, compared to vegetable essential oils or spices, are like missiles, fighting only pathogens, while the latter is like chemical weapons, which, whether harmful or harmless, negatively affect all living cells. Making the environment better and improving the safety and cleanliness of the feed raw materials themselves is the fundamental solution to the ban on antibiotics. In the process, there must be a transition, the programme is a combination of alternative expediency and transition altogether, these means are effective, at this stage is also necessary, but seems imperfect, each with inherent defects, the implementation of which needs attention.is it feasiblex4E
alternative antibiotics to veterinary drugs?x4E
from North America to the European Union, where the breeding authorities are busy banning resistance, as a major aquaculture country, our ban horn has also been sounded. After discussion and some screening, Chinese veterinary drugs have become a more suitable alternative antibiotics x4E
from a policy level, the prohibition of antibiotics policy and related regulations recently issued, this is the prohibition in our country,is also the beginning, will eventually be transmitted to the grass-roots first line of each relevant corner. As early as 2016, the introduction of the "Chinese veterinary drugs, natural drugs premix general technical requirements (draft) draft", promoting the registration of Chinese veterinary drugs as drug additives. At present, many large-scale livestock and poultry breeding enterprises have taken Chinese veterinary drugs as the prevention, treatment of diseases and promote animal growth of the focus of the use of objects. x4E
from the pharmaceutical level, Chinese veterinary medicine is a kind of Traditional Chinese medicine, the current market demand for Chinese veterinary medicine is mainly concentrated in the following categories: First, with antibacterial effects of Chinese medicine, such as jaundice, jaundice, fishy grass, heart lily, etc. ; Traditional Chinese medicine, mainly for the elimination of spleen, such as hawthorn, malt, chenskin, and with its formula to complement the beneficial gas, such as white art, licorice, yellow sperm, etc. ; It can be seen that for the current wide variety of livestock diseases, the current category of veterinary drugs is difficult to cope with. In addition, there is whether Chinese veterinary drugs can be used for a long time, but also to be verified by practice. x4E
the stability of Chinese medicine is relatively poor compared to chemicals. The origin of medicine, collection method, medicinal parts, processing methods, concocting methods, use of dosages, different methods of distribution, etc. will affect the effect of Traditional Chinese medicine. At the same time, chinese medicine preparations also have some limitations, raw material mold also troubled the development of the industry. x4E
different taste of Chinese medicine, long-term continuous use of biased Chinese medicine may cause changes in the animal body. For example, the long-term use of cold drugs (clear heat), will cause the body's yang shortage, water drop, drop in food harvest, mental depression and other symptoms of impotence; Different Chinese medicine on livestock and poultry harvest also has an impact, cold class will reduce the amount of food, warm spleen can improve the amount of food. The effect of weak bias on the amount of food harvest is not significant, and the use period can be longer. Chinese medicine with strong bias can not be used for a long time, even should not be used for more than 7 days. Heat-clearing drugs can reduce the body's immune response, continuous use should not exceed 5 days. All of these limitations of Chinese medicine deserve the attention of the industry. How x4E
how to deal with veterinary drug residues in China? x4E
of course, The Chinese veterinary drug itself has some problems of its own, drug residues are the biggest problem, January 9, the Ministry of Agriculture and Rural Affairs and the National Health And Health Commission, the State Administration of Market Supervision and Administration jointly issued the "National Standards for Food Safety
the maximum residue limit of veterinary drugs in food", will be implemented from April 1, 2020. x4E
the largest residue limit standard of veterinary drugs in the food released this time stipulates 267 kinds of veterinary drugs in livestock and poultry products, aquatic products, bee products in the 2191 residual limit and use requirements, basically covering China's commonveterinary drug species and major food animals and tissues, marking China's veterinary drug residue standard system construction into a new stage. x4E
reported that the new standards cover veterinary drug species and limits of a significant increase. Compared with the previously issued Ministry of Agriculture announcement No. 235 "maximum residue limit of veterinary drugs in animal food", the new standard provides for an increase of 76 kinds of veterinary drugs, an increase of 39.8%, a residue exemption variety increased by 66 species, an increase of 75%, the residue limit increased by 643 items, an increase of 41.5%, basically solved the current evaluation of animal food "limited standard snot." x4E
the newly released standards fully adopt the CAC and the European Union, the United States and other developed countries and regions of the most stringent standards, the Ministry of Agriculture Announcement No. 235 involved in the residual markers, daily allowable intake, residual limit value, use requirements and other important technical parameters have been comprehensively revised, set the residual limit value and CAC veterinary drug residue limit value consistent with the CAC veterinary drug residue value of more than 90% or more; x4E
Chinese veterinary drugs in the anti-viral, improve immunity, anti-stress and promote growth and development of the advantages, so that many enterprises optimistic about the development prospects of Chinese veterinary drugs. But even if the current momentum of development of Chinese veterinary drugs is in full swing, giving full play to the role of Chinese veterinary drugs in livestock and poultry breeding has a long way to go. x4E
some Chinese veterinary drug manufacturers to add Western ingredients to Chinese veterinary drugs to produce Chinese and Western synthetic drugs, so that consumers have doubts about the entire market. According to relevant reports, the proportion of Chinese veterinary drugs in counterfeit veterinary drugs is quite large. As a drug, the standard use of Veterinary medicine is very important, in the future for a period of time, to replace all antibiotics at once is not very realistic. x4E .