Circulation: A child's prognosis for acute heart failure after contracting the new coronavirus.

As of 15 p.m. on August 6, 2020, a total of 18,984,976 cases of new coronavirus infection have been confirmed worldwide, and the United States, India and Brazil have maintained a very high rate of new growth (each adding 50,000 plus in the last 24 hours).
worse, the World Health Organization warns that the new crown may never have a "special effects drug"! Now, the sequelae of the new crown infection is emerging, such as pulmonary fibrosis, kidney failure, cerebral hemorrhage, stroke and muscle atrophy.
, heart muscle damage and myocarditis were observed in many adult patients with new coronavirus infection.
in children, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection usually has mild symptoms.
but Belhadjer et al. found that a range of hyperthertic pediatric patients with acute heart failure may be associated with SARS-CoV-2 infection and multisystem inflammatory syndrome.
two months after the SARS-CoV-2 pandemic broke out in France and Switzerland, Belhadjer et al. retrospectively collected clinical, biological, therapeutic and early prognostic data on 35 children in the pediatric intensive care unit who were admitted to the pediatric intensive care unit at 14 medical centers for heart-induced shock, left heart insufficiency and severe inflammation.
the median age of children included in the study was 10 years (2-16 years old).
28% of underlying diseases, including asthma and overweight.
clinical manifestations: gastrointestinal symptoms are prominent.
1/3 of children with left ventricular blood score was 30;30%, 80% needed strong heart medication support, and 28% of the children received in vitro pulmonary oxygenation treatment.
inflammatory markers suggest cytokine storms (IL-6 median: 135 pg/ml) and macrophage activation (D-dipolymer median: 5284 ng/mL).
increased average level of type B sodium urethred (BNP) (5743 pg/mL).
31 (88%) of children tested positive for their new crowns.
all children receive immunoglobulin therapy, and one third of the children receive complementary steroid therapy.
left ventricular function of 25 children was restored when they were out of the intensive care unit.
no patients died, and all children treated with in vitro pulmonary oxygenation successfully switched to autonomous respiration.
in general, after SARS-CoV-2 infection, children may suffer from severe inflammatory conditions that can lead to acute cardiac failure.
immunoglobulin therapy may be related to the restoration of left ventricular function.
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