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Marra and his colleagues presented some interesting data about the course of syphilis in people who had previously experienced syphilis
.
Based on the data of 651 patients with syphilis, 169 of whom have had syphilis before, it is concluded that a previous history of syphilis can reduce the symptoms of subsequent syphilis infection
Infect
The article shows the results of univariate and multivariate analysis of the correlation between six key variables and the detection of Treponema pallidum DNA in blood or rRNA in cerebrospinal fluid (CSF)
.
A prominent factor is: received syphilis treatment before entering the study, the adjusted OR (AOR) for DNA detection in blood was 0.
In view of this, the conclusion that Treponema pallidum DNA is more rare in blood and rRNA CSF in the index period than those without a history of syphilis may be untenable
.
While we agree "acquired syphilis episodes originally produced by immunization will influence the performance of the subsequent onset and course of syphilis," this assumption, but it can not be concluded based on the current analysis
immunity
Source: Schim van der Loeff MF, Zondag H, Bruisten S, Does Previous Syphilis Alter the Course of Subsequent Episodes of Syphilis? Clin Infect Dis 2021 Sep 21
Schim van der Loeff MF, Zondag H, Bruisten S, Does Previous Syphilis Alter the Course of Subsequent Episodes of Syphilis? Clin Infect Dis 2021 Sep 21Leave a message here
