Clin Microbiol Infect: Pneumonia is a common co-existing infection in patients with bacterial meningitis and is associated with adverse outcomes

Pneumonia is a common concomitent infection in patients with community-based bacterial meningitis, but the impact on the course of the disease is unclear.
forward-looking study, which explores the characteristics, clinical processes and outcomes of pneumonia when meningitis patients are admitted to hospital, has been published online in Clin Microbiol Infect.
assessed adult patients with community-based bacterial meningitis who were admitted with pneumonia between March 2006 and June 2017.
a logical regression analysis to determine the clinical characteristics of pneumonia at the time of hospitalization and to quantify the effects of pneumonia on outcomes.
results showed that 315 (17%) of the 1852 cases (17%) of bacterial meningitis were diagnosed with pneumonia upon hospitalization, and 256 (83%) of the 308 cases (83%) were diagnosed with pneumonia by chest X-ray.
256 (81%) of the 315 cases were Streptococcus pneumoniae infections.
multivarivity analysis shows pneumonia and old age at hospital (OR increases by 1.03, 95% CI 1.02-1.04, P<0.001), alcoholism (OR 1.96, 95% CI 1.23-3.14, P 0.004), cancer (OR 1. 54,95% CI 1.12-2.13, P 0.008), no otitis otitis or sinusitis (OR 0.44, 95% CI 0.32-0.) 59, P .lt;0.001) and pneumococcal (OR 2.14,95% CI 1.55-2.95, P .lt;0.001).
observed adverse results of 1-4 on the Glasgow result scale in 172 (55 per cent) patients, with 87 (28 per cent) deaths.
in a multivariable analysis, pneumonia was independently associated with adverse outcomes and death at the time of hospitalization (OR 1.48, 95% CI 1.12-1.96; P 0.005).
, the results show that pneumonia is a common side-by-side infection in patients with bacterial meningitis and is independently associated with adverse outcomes and death.
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