Cobweb subcavity expansion predicts intra-brain hemorrhage expansion

Previous studies have shown that cobweb subcranial dilation (subarachnoid extension, SAHE) in patients with cerebral hemorrhage (ICH) is independently associated with deterioration of nerve function and poor prognosisSingle-center retrospective analysis suggests that SAHE increases the risk of hematoma expansion (hematoma expansion, HE)Andrea Morotti of the IRCCS Fondazione Neurology In Pavia Monteno, Italy, and others studied the correlation between SAHE and HE in the brain lobe, published online march 2020Research Methodsresearchers combined data from patients with primary ICH who were admitted to three academic medical institutions in Italy, aged 18 years old, had clinical symptoms, or were stable after 48 hoursPatients must have high-quality baseline CT flat sweep and follow-up CT flat sweep imagesExclude (1) intra-brain hemorrhage that is inherited from trauma, vascular malformations, tumors or other etiology; (2) primary intracrany hemorrhage; (3) lack of imaging data; (4) hematoma removal prior to follow-up CT; (5) ischemic stroke bleeding; and (6) patients in intensive care or neurosurgery wardsSpontaneous ICH patients were divided into study and control groups, and SAHE was evaluated based on baseline CT flat-sweep images by four researchers who did not know about the groupA typical image of CT flat sweep with intracranthary hemorrhage accompanied by subcranline expansion of the cobweb spandation is shown in Figure 1Figure 1CT flat sweep image of intra-brain hemorrhage with subcranline expansion of cobweb membraneABaseline CT flat sweep shows intracrany hemorrhage associated with subcranline expansion of the cobweb (arrow);results
the study's main prognosis indicator is HE, which refers to the absolute volume of ICH increased by 6mL or ICH relative volume increaseby of 33% from baseline to follow-up CT sweepMultivariate logistic regression of the ICH site (intra- and non-brain leaf) stratified was used to evaluate the prediction factors of HEThe results showed that 360 cases and 192 patients were included in the study group and control group respectively Unwitting researchers identified SAHE reliability (K-0.82), with SAHE at 27.8% in the study group and 24.5% in the control group Single-variable analysis suggested that HE was more common in patients with intra-brain hemorrhage with SAHE (52.0%:27.3% ;P 0.001) Multivariate logistic regression analysis, after correcting potential confounding factors, showed that SAHE was an independent predictor of intra-brain hemorrhage (OR s 6.00; 95% CI, 2.16-16.64; P-0.001), while SAHE was not associated with HE with non-brain-leaf ICH (OR-0.55; 95% CI, 0.17-1.84; An increased risk of HE risk in the cerebral loe ched with SAHE was seen in the control group (OR s 3.46; 95% CI, 1.07-11.20; P-0.038) Conclusions
the results show that SAHE is common in CT flat-sweeps in patients with acute spontaneous ICH, and That SAHE can predict THE HE of ICH in the brain lobe Identifying SAHE requires only baseline CT sweep, which helps to analyze HE risk through simple methods in clinical practice in order to grasp the trend of disease development.