Crit Care: Causes and characteristics of death in patients with acute hypoxemia respiratory failure and acute respiratory distress syndrome

!---- acute hypoxemia respiratory failure (AHRF) and acute respiratory distress syndrome (ARDS) are associated with mortality in the high court, however, in the 1990s, it was more common for patients to die of sepsis or multiple organ failure rather than refractive hypoxemiaOver the past 25 years, researchers hypothesized that the causes of death in contemporary patients may differ, as more and more attention has been paid to the treatment of pulmonary protection ventilation and sepsisthese differences can provide a reference for clinicians in therapeutic interventionsresearchers identified adult patients admitted to a single tertiary medical centre (2016-2017), and AHRF is defined as PaO2/FiO2 s 300, while receiving invasive mechanical ventilation of 12h and dying during hospitalizationphysicians ruled on the absence of ARDS based on the Berlin definitionIndependent abstracterswho did not understand the status of ARDS used standardized tools to collect data on organ dysfunction and withdrawal of life supportThe leading cause ofdeath is defined as the organ system that directly causes death or withdrawal of life supportresearchers identified 385 deaths with AHRF, 127 (33%) of whom had ARDSthe most common causes of deathwere sepsis (26%), pulmonary insufficiency (22%) and neurological insufficiency (19%)death had a 70% incidence of multiple organ failure, the most common cause was sepsis (50% of all patients), and 70% of patients needed respiratory support at the time of deathonly 2% of patients do not need oxygen or ventilation85% of patients die after stopping life supportARDS patients are more likely to die with pulmonary dysfunction as the primary cause of death (28% vs 19% ;p s 0.04) and more likely to die if they require significant respiratory support (82% vs 64% ;p .lt;0.01) the most common causes of death in this contemporary AHRF patient queue are sepsis and pulmonary dysfunction the vast majority of deaths occur after evacuation stake patients with ARDS are more likely to die with pulmonary dysfunction and require significant respiratory support than patients without ARDS