Diabetes: Incidence of insulin-dependent hyperglycemia syndrome in young individuals infected with SARS CoV-2

Background: While respiratory failure, cardiovascular pathology, and thrombotic events are the most common causes of severe morbidity and mortality in patients with coronavirus disease 2019 (COVID-19), multiple organs are present in infected individuals, including the pancreas.

Background: While respiratory failure, cardiovascular pathology, and thrombotic events are the most common causes of severe morbidity and mortality in patients with coronavirus disease 2019 (COVID-19), multiple organs are present in infected individuals, including the pancreas.

Although recent data suggest that glucose metabolism control is disturbed after Covid-19 treatment, other findings suggest that the incidence of insulin-requiring diabetes in Covid-19 patients (without any history of diabetes) is no higher than that reported in the general population (based on the U.

Therefore, for the first time, we provide population-level data on global healthcare organizations showing the incidence of diabetes reflecting T1D in COVID-19 patients, particularly historically and epidemiologically showing the highest risk and incidence of beta-cell autoimmunity There was no difference in the incidence among age-matched non-coronavirus-infected individuals in age groups with rates up to 30 years old

Methods: We investigated the incidence of T1D in patients with COVID-19 in a large global population using a 'big data' approach

RESULTS: Among people under the age of 18, the incidence of diabetes requiring insulin therapy (representing T1D) was not statistically different in patients with confirmed Covid-19 compared with the non-COVID-19 control group

Table 1 Age and sex of patients in the age-stratified cohort

Table 2 Incidence of type 1 diabetes (T1D) in propensity score-matched patients without type 2 diabetes

Table 2 Incidence of type 1 diabetes (T1D) in propensity score-matched patients without type 2 diabetes

Table 3 Incidence of type 2 diabetes (T2D) in propensity score-matched patients without type 1 diabetes

Table 3 Incidence of type 2 diabetes (T2D) in propensity score-matched patients without type 1 diabetes

CONCLUSIONS: Therefore, asymptomatic virus-infected patients may still acquire β-cell autoimmunity and eventually progress to dysglycemia and clinical T1D with a high incidence

CONCLUSIONS: Therefore, asymptomatic virus-infected patients may still acquire β-cell autoimmunity and eventually progress to dysglycemia and clinical T1D with a high incidence

Original source:

 Pietropaolo M, Hotez P, Giannoukakis N, Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS CoV-2-Infected Young Individuals: Is it Type 1 Diabetes? Diabetes 2022 Mar 16

 Pietropaolo M, Hotez P, Giannoukakis N,Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS CoV-2-Infected Young Individuals: Is it Type 1 Diabetes?Diabetes 2022 Mar 16Leave

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