Eating more may increase the risk of dementia Trans fats and add "sinful"

It is well known that excessive intake of trans fats is associated with the development of coronary heart disease and diabetesNow, there may be another addition to the trans fat's harm list: dementiaA new study published by researchers at Kyushu University in Japan in the Journal of the American Academy of Neurology, Neurology, shows that people with higher levels of trans fat in their blood are more likely to develop dementia in later lifethe data from the new study comes from the Prospective Cohort Study, the Hisayama StudyThe Hisayama study collected blood samples and health information from 1,628 people in 2002-2003, all aged 60 and over, and did not develop dementiaat the beginning of thestudy, the researchers measured trans oleic acid levels in their serum, which are the main trans fats formed when vegetable oil is hydrogenated, and whose serum levels are considered an indicator of trans fat intakeAccording to this indicator, the subjects were divided into four groupsThe subjects were also screened for dementia in 2005 and 2012, including subtypes such as Alzheimer's disease and vascular dementiaan average of 10.2 years of follow-up, a total of 377 subjects developed dementia, including 247 cases of Alzheimer's disease and 102 cases of vascular dementiaadjusted for variables such as high blood pressure, diabetes, current exercise levels, and smoking, the researchers found that overall, the risk of developing dementia increased significantly as trans fat levels in the serum increasedPeople with the highest levels of trans oleic acid increased their risk of dementia by 52 per cent compared to those in the lowest group, and the second-highest group had a 74 per cent increased risk of developing dementia, which appeared to be more affectedThe findings were similar to those found in The Breakdown of Alzheimer's disease and vascular dementiaThese associations were still evident after continuing to adjust the total calorie intake, saturation and intake of polyunsaturated fatsat the start of the study, the study covered the intake of 150 foods in 23 categoriesThe researchers focused on seven of the foods that contain trans fats, including cereals, sweets, animal and plant fats, sugars and sweeteners, seasonings, meats and dairy productsThe study found that desserts were the foods that were most likely to cause elevated levels of trans oleic acid in the serum, followed by margarines and sugars such as candy, caramel and chewing gumIn addition, croissants, non-dairy cream, ice cream and rice cakes are also associated with higher trans oleic acid levels in the serumstudies suggest that avoiding trans fat-rich foods may reduce the risk of dementia in the futureThe researchers also point to limitations in the study, such as measuring trans oleic acid levels in only one serumPeople's diets vary widely from region to region, and further research is needed on people outside Japan"This adds a new reason for our rejection of trans fats," said DrToshiharu Ninomiya of Kyushu University, aresearch leaderIn 2018, who called for the global food supply to discontinue industrially produced trans fats, and developed guidance to eliminate these harmful compounds by 2030There is not enough evidence to determine whether trans fats in naturally occurring foods are equally harmfuldrKlodian Dhana of Rush University Medical Center in Chicago said: "Because trans oleic acid is an exogenous fatty acid, when you buy a packaged food, it is necessary to check that the nutrition label is labeled '0 g trans fat' and that there is no hydrogenated oil in the ingredient list." It is recommended to replace trans fats with healthier unsaturated fats, such as monounsaturated fats and polyunsaturated fatsIncreased intake of foods that are beneficial to brain health, especially green leafy vegetables, berries, whole grains, fish, poultry, nuts and olive oil, should be restricted, and red meat, fried foods, pastries and sweets should be restricted"
ReferencesSerum e elaidic acid and risk of dementiaNeurology, DOI: 10.1212 / WNL.0000000000000008464 2' Dementia Tied to Trans Fats - Alzheimer's Links all-cause dementia and's to higher levels of elaidic acid Retrieved Oct 28, 2019, from https:// Retrieved Oct 28, 2019, from https://#vp_1