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    Home > Active Ingredient News > Anesthesia Topics > Effects of delirium and perioperative stroke on long-term outcomes in patients with high-scoring literature reading and surgical aortic valve replacement

    Effects of delirium and perioperative stroke on long-term outcomes in patients with high-scoring literature reading and surgical aortic valve replacement

    • Last Update: 2022-09-30
    • Source: Internet
    • Author: User
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    The impact of perioperative stroke and delirium on outcomes after surgical aortic valve replacement

    Effects of delirium and perioperative stroke after surgical aortic valve replacement on long-term outcomes in patients







    By Dani & Miao & Cat


    Abstract



    The effect of stroke and delirium on discharge cognition and health outcomes in patients with surgical aortic valve replacement (SAVR) is unclear
    .

    Therefore, we aim to investigate the effects
    of perioperative stroke and delirium on patient-centered health outcomes at 90 days postoperatively.


    Methods: SAVR patients (N=383) (41% who also underwent coronary bypass grafting) were enrolled to undergo neurological function and delirium assessment at 1, 3, and 7 days after surgery, and MRI examination
    at 7 days.

    Outcomes included a 90-day change in functional levels and neurocognitive decline compared to preoperative changes
    .


    Results: 25 (6.
    6%) patients had clinical stroke and 103 (28.
    5%) developed delirium
    .

    Perioperative stroke patients and delirium patients (HR, 0.
    68; 95% [CI]:0.
    54-0.
    86; P 1/4.
    001) experienced a longer hospital stay (HR, 0.
    62; 95%[CI]:0.
    42-0.
    94; P 1/4.
    02) Patients with delirium (HR, 0.
    68; 95%[CI]:0.
    54-0.
    86; P ¼ .
    001)

    Stroke patients with 90 days were more likely to score on the modified Rankin scale >2, [OR], 5.
    9; 95%[CI]:1.
    7-20.
    1; P 1/4.
    01), more depressed (OR, 5.
    3; 95% [CI]:1.
    6-17.
    3; P 1/4 .
    006), lower adjusted mean difference P 1/4 .
    08), postoperative cognitive decline (OR, 7.
    8; 95% [CI]:2.
    3-26.
    4; P ¼ .
    001)



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