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    Home > Active Ingredient News > Antitumor Therapy > Eur Radiol: A fast and accurate MRI program to diagnose colorectal cancer liver metastasis!

    Eur Radiol: A fast and accurate MRI program to diagnose colorectal cancer liver metastasis!

    • Last Update: 2021-02-24
    • Source: Internet
    • Author: User
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    Colorectal cancer (CRC) is a major public health problem and the world's third-largest cause of cancer death.
    about 50% of colorectal cancer patients are accompanied by liver metastasis, with or without liver metastasis will affect the formulation of treatment strategies.
    , accurate diagnosis of liver metastasis is essential.
    , computer fault scanning (CT) is considered the most commonly used imaging method for diagnosing liver metastasis.
    recent studies have shown that magnetic resonance imaging (MR imaging) has been shown to be superior to CT in the detection and characteristic display of liver lesions, especially when the lesions are too small to be clearly displayed on CT.
    addition, the introduction of liver-specific contrast agents further improved the diagnostic performance of MR imaging.
    some studies and Mate analysis have shown that MR imaging with liver-specific contrast agents is significantly better than CT and MR imaging with extracellular contrast agents.
    clinical MRI standard sequences include dispersion-weighted sequences, dynamic enhancement sequences (arterial, gate vein, and equilibrium), liver and bile (HPB), and so on.
    recent studies suggest that a shorter option that does not include dynamic enhancement sequences may be a faster and more convenient alternative to evaluating colorectal liver metastasis.
    will help address the increasing demand for liver MR during initial patient examinations and follow-up.
    Recently, a study published in the Journal of European Radiology compared the standard and simulated "short" niobium disodium-enhanced MRI program to evaluate the performance of colorectal cancer liver metastasis (CRLM), and proposed a short program that is comparable to the diagnostic performance of the standard MRI program while being faster and more convenient, so that imaging can better serve the clinical community.
    study included 67 colorectal cancer patients (44 men (66%) between 2008 and 2017; With an average age ±65 years and 11 years of age), each patient under the initial test for colorectal cancer under the MRI-enhanced nitrate.
    These tests were evaluated independently by two readers who were not aware of clinical data in two reading sessions: (1) the sequence obtained from all acquisitions (standard "long" scheme) and (2) only T2-weighted, dispersed weighted and liver and bile period images (simulated "short" scenarios).
    readers used a 5-point system (1 must be benign -5 must be malignant) to describe the lesions found.
    when the lesion score ≥ 3, the disease was determined to be CRLM.
    reference criteria are histological pathological results or 12-month imaging follow-up.
    are compared with the card-side test, the Student's test, and the McNemar test.
    486 lesions were analysed, including 331 metastasis (68 per cent).
    detection rate of short-term and long-term schemes is 86.1% (95% CI 82 to 89.4) to 86.7% (82.6 to 90) and 85.8% (81.6 to 89.2) to 87% (82.9 to 90.2) (p2.9 to 90.2) 0.99).
    the detected lesions, 92.1% (89.1-94.4) to 94.8% (92.2-96.6) and 84.6% (80.8-87.7) to 88.8% (85.4-91.5) (p s 0.13 and p s 0.10) lesions.
    when the lesions score ≥ 4 points was determined to be CRLM, the results remained the same.
    1 scores lesions in liver lesions detected using two scenarios.
    shown in the figure, the transfer rate of short and long schemes is comparable. Table
    1 This study shows that the diagnostic performance of analog short-enhanced MR schemes, including T2-weighted, dispersed weighted, and liver and bile phase images, is similar to that of standard long-term scenarios, including dynamic period images.
    the program shortens the time of MR examination, it can make the assessment of liver metastasis in colorectal cancer patients faster and more convenient.
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