Eur Radiol: What are the characteristics of T1-weighted image texture analysis in patients with peroneal muscular atrophy?

 

 

Skeletal muscle magnetic resonance imaging (MRI) is a clinically commonly used non-invasive imaging technique to assess muscle involvement in neuromuscular diseases.

Skeletal muscle magnetic resonance imaging (MRI) is a clinically commonly used non-invasive imaging technique to assess muscle involvement in neuromuscular diseases.

Texture analysis is an image analysis method used to detect and quantify the heterogeneity of tissue features, which has a higher sensitivity than visual evaluation.

Peroneal muscular atrophy (CMT) is the most common hereditary polyneuropathy, which is characterized by an insidious onset, mainly manifested by distal muscle atrophy, loss of movement and sensory.

Recently, a study published in the journal European Radiology explored the correlation between the texture features of T1-weighted images and the fat scores obtained by quantitative fat imaging, and at the same time evaluated its potential for detecting lesions by comparing the texture features of healthy volunteers and CMT patients .

To explore whether the texture features of T1-weighted images are related to fat scores, and whether they are different between patients with peroneal muscular atrophy (CMT) and healthy volunteers.

To explore whether the texture features of T1-weighted images are related to fat scores, and whether they are different between patients with peroneal muscular atrophy (CMT) and healthy volunteers.

This retrospective study was approved by the institutional review board, and the requirement for informed consent was waived.

 

Figure 1 Scatter plot of the relationship between texture features and fat scores of 407 muscles.

Figure 1 Scatter plot of the relationship between texture features and fat scores of 407 muscles.

Figure 2 Box plots of average (a), SD (b), skewness (c), kurtosis (d) and entropy (e) of signal intensity on T1-weighted images of healthy volunteers and CMT patients.

Figure 2 Box plots of average (a), SD (b), skewness (c), kurtosis (d) and entropy (e) of signal intensity on T1-weighted images of healthy volunteers and CMT patients.

This study shows that the texture features of T1-weighted images are correlated with fat scores, indicating that these features have the potential to quantify the degree of intramuscular fat infiltration, and there are differences between CMT patients and healthy volunteers, providing an early diagnosis for the clinic And non-invasive imaging methods for disease monitoring.

Original source:

Ji Hyun Lee,Young Cheol Yoon,Hyun Su Kim,et al.

Ji Hyun Lee,Young Cheol Yoon,Hyun Su Kim,et al.
Texture analysis using T1-weighted images for muscles in Charcot-Marie-Tooth disease patients and volunteers.
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