Eur Radiol: What is the novelty of cone beam breast CT in evaluating breast cancer?

Breast cancer is the most common cancer and the main cause of death among women worldwide.

Breast cancer is the most common cancer and the main cause of death among women worldwide.

Although IHC is the gold standard for evaluating molecular subtypes, it also has some limitations.

Breast cancer enhanced cone beam breast CT (contrast-enhanced cone beam breast CT, CE-CBBCT) can simultaneously provide lesion morphology, calcification and quantitative hemodynamic characteristics, making it possible to predict the molecular subtype of breast cancer.

Recently, a study published in the journal European Radiology explored the imaging features of invasive breast cancer on CE-CBBCT, and compared its relationship with IHC receptor status and molecular subtypes, providing a clinical perspective.

All patients included in this retrospective study underwent CE-CBBCT examination and received complete immunohistochemical analysis before surgery .

All patients included in this retrospective study underwent CE-CBBCT examination and received complete immunohistochemical analysis before surgery .

A total of 211 female patients were enrolled in this study , and a total of 240 cases of invasive cancer were diagnosed.

Figure shows examples of four subtypes of breast cancer on NCE-CBBCT and CE-CBBCT images.

Figure shows examples of four subtypes of breast cancer on NCE-CBBCT and CE-CBBCT images.

CE-CBBCT features help predict the status of IHC receptors and distinguish the molecular subtypes of breast cancer, thereby helping to make individualized treatment decisions and prognostic predictions.

Original source:

Yue Ma,Aidi Liu,Avice M O'Connell,et al.

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