Expansion of the reference genome map of the human gut microbiome reveals hundreds of unknown species

Nature Communications [IF:1694] ① Combining the newly assembled MAGs from more than 50,000 metagenomic samples with the existing human gut microbiota genomes, a set of 241,118 genomes (WIS dataset) was constructed; ② The WIS contains 3,594 species belonging to 628 families , 2365 genera, 310 species and 19 genera were newly discovered; ③ Compared with the two existing human gut genome sets, WIS has higher genome quality, alignment rate, and more genomes than UHGG and UNITN Coding regions and low-abundance species; ④ Some new species in WIS exist in more than 15% of the samples, and can also be used as differential markers for different cohorts; ⑤ Compared with known species, new species have lower potential resistance to antibioti. An expanded reference map of the human gut microbiome reveals hundreds of previously unknown species07-05, doi: 11038/s41467-022-31502-1 【Editor-in-chief】With the development of sequencing technology and bioinformatics, researchers can learn from metagenom. The samples were continuously assembled to restore the gut microbiota genome, and a number of human gut microbiota genome reference datasets were construct. Recently, researchers published their latest study in Nature Communicatio. By combining newly assembled MAGs from more than 50,000 metagenomic samples with the existing human gut microbiota genome, a dataset of more than 240,000 genomes (WIS data) was construct. set), revealing hundreds of unknown speci. This dataset is of higher quality and richer in low-abundance species than the current UHGG and UNITN datase. In conclusion, the WIS dataset further expands the reference genome map of human gut microbiota, which is worthy of testing and comparison by relevant personn. (@jiuqingchen)   Disclaimer: This article only represents the author's personal opinion and has nothing to do with China Probiotics Netwo. Its originality and the text and content stated in the text have not been verified by this site, and this site does not make any guarantee or commitment to the authenticity, completeness and timeliness of this text and all or part of its content and te. Readers are only for reference and please Verify the relevant content yourse. Copyright Notice Some articles reproduced on this site are not original, and their copyright and responsibility belong to the original auth. All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and the source and author are clearly indicat. Media or individuals who do not wish to be reprinted can contact us for infringing information that can provide sufficient eviden. , bio149 will be deleted within 12 hours after confirmati. Users are welcome to submit original articles to 86371366@. com, which will be published on the homepage after review, and the copyright and responsibility of the articles belong to the send.

Nature Communications
① Combining the newly assembled MAGs from more than 50,000 metagenomic samples with the existing human gut microbiota genomes, a set of 241,118 genomes (WIS dataset) was constructed; ② The WIS contains 3,594 species belonging to 628 families , 2365 genera, 310 species and 19 genera were newly discovered; ③ Compared with the two existing human gut genome sets, WIS has higher genome quality, alignment rate, and more genomes than UHGG and UNITN Coding regions and low-abundance species; ④ Some new species in WIS exist in more than 15% of the samples, and can also be used as differential markers for different cohorts; ⑤ Compared with known species, new species have lower potential resistance to antibioti.
An expanded reference map of the human gut microbiome reveals hundreds of previously unknown species07-05, doi: 11038/s41467-022-31502-1 【Editor-in-chief】With the development of sequencing technology and bioinformatics, researchers can learn from metagenom.
The samples were continuously assembled to restore the gut microbiota genome, and a number of human gut microbiota genome reference datasets were construct.
Recently, researchers published their latest study in Nature Communicatio.
By combining newly assembled MAGs from more than 50,000 metagenomic samples with the existing human gut microbiota genome, a dataset of more than 240,000 genomes (WIS data) was construct.
set), revealing hundreds of unknown speci.
This dataset is of higher quality and richer in low-abundance species than the current UHGG and UNITN datase.
In conclusion, the WIS dataset further expands the reference genome map of human gut microbiota, which is worthy of testing and comparison by relevant personn.
(@jiuqingchen)

---

Nature Communications
① Combining the newly assembled MAGs from more than 50,000 metagenomic samples with the existing human gut microbiota genomes, a set of 241,118 genomes (WIS dataset) was constructed; ② The WIS contains 3,594 species belonging to 628 families , 2365 genera, 310 species and 19 genera were newly discovered; ③ Compared with the two existing human gut genome sets, WIS has higher genome quality, alignment rate, and more genomes than UHGG and UNITN Coding regions and low-abundance species; ④ Some new species in WIS exist in more than 15% of the samples, and can also be used as differential markers for different cohorts; ⑤ Compared with known species, new species have lower potential resistance to antibioti.

An expanded reference map of the human gut microbiome reveals hundreds of previously unknown species07-05, doi: 11038/s41467-022-31502-1 【Editor-in-chief】With the development of sequencing technology and bioinformatics, researchers can learn from metagenom.

The samples were continuously assembled to restore the gut microbiota genome, and a number of human gut microbiota genome reference datasets were construct.

Recently, researchers published their latest study in Nature Communicatio.

By combining newly assembled MAGs from more than 50,000 metagenomic samples with the existing human gut microbiota genome, a dataset of more than 240,000 genomes (WIS data) was construct.

set), revealing hundreds of unknown speci.

This dataset is of higher quality and richer in low-abundance species than the current UHGG and UNITN datase.

In conclusion, the WIS dataset further expands the reference genome map of human gut microbiota, which is worthy of testing and comparison by relevant personn.

(@jiuqingchen)

---

Nature Communications Nature Communications[IF:1694]① Combining the newly assembled MAGs from more than 50,000 metagenomic samples with the existing human gut microbiota genome, a set of 241,118 genomes (WIS dataset) was constructed; ② WIS contains 3,594 species, It belongs to 628 families and 2365 genera, and 310 species and 19 genera are newly discovered; ③ Compared with the two existing human intestinal genome collections, WIS has higher genome quality and alignment rate than UHGG and UNITN , more genome coding regions and low-abundance species; ④ Some new species in WIS exist in more than 15% of the samples, and can also be used as differential markers for different cohorts; ⑤ Compared with known species, new species have potential for antibiotics lower resistan.

An expanded reference map of the human gut microbiome reveals hundreds of previously unknown species07-05, doi: 11038/s41467-022-31502-1 【Editor-in-chief】With the development of sequencing technology and bioinformatics, researchers can learn from metagenomic The samples were continuously assembled to restore the gut microbiota genome, and a number of human gut microbiota genome reference datasets were construct.

Recently, the researchers published their latest study in Nature Communicatio.

By combining newly assembled MAGs from more than 50,000 metagenomic samples with the existing human gut microbiota genomes, a dataset of more than 240,000 genomes (WIS data) was construct.

set), revealing hundreds of unknown speci.

This dataset is of higher quality and richer in low-abundance species than the current UHGG and UNITN datase.

In conclusion, the WIS dataset further expands the reference genome map of human gut microbiota, which is worthy of testing and comparison by relevant personn.

(@jiuqingchen)

---