Expert Rev Anti Infection Sr: Probiotic and cranberry supplements prevent recurrent simple urinary tract infections in premenopausal women

The purpose of this study is to evaluate the efficacy and safety of Bio-Kult Pro-Cyanthis is a randomized, double-blind, placebo-controlled trialThe subjects received BKPro-Cyan or a placebo twice a day for 26 weeksThe main endpoint was the proportion of subjects who relapsed UTI at the end of the studyA total of 115 subjects were screened; 90 were in the group; and 81 participants completed the studyAfter 26 weeks, the number of women who relapsed UTI decreased significantly compared to placebo sauors (9.1 vs 33.3%; P - 0.0053)Compared to placebos, BKPro-Cyan produced statistically significant improvements in multiple secondary endpoints, including: more subjects without UTIs (90 vs 67%; P .05); first UTI is longer (174 vs 90 days; P - 0001); short active UTI duration (5 vs12 days; P - 0.009); fewer subjects requiring antibiotic treatment (3 vs 11; Presults show edited that BKPro-Cyan is safe and effective in preventing recurrent UTI in premenopausal adult womenThese findings support the need for further designed trials to identify possible benefits