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    Home > Active Ingredient News > Study of Nervous System > Express delivery across the blood-brain barrier!

    Express delivery across the blood-brain barrier!

    • Last Update: 2022-09-07
    • Source: Internet
    • Author: User
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    ▎Edited by WuXi AppTec Content Team

    Denali Therapeutics today announced new interim results from a Phase 1/2 clinical trial of its investigational enzyme replacement therapy DNL310 in mucopolysaccharidosis type II (MPS II, also known as Hunter syndrome)



    MPS II is a rare neurodegenerative lysosomal storage disease caused by mutations in the gene encoding human idose-2-sulfatase (IDS), affecting more than 2,000 patients worldwide


    ▲Denali’s transporter platform (Image source: Denali’s official website)


    WuXi AppTec provides integrated, end-to-end new drug R&D and production services for the global biopharmaceutical industry, covering chemical drug R&D and production, biological research, preclinical testing and clinical trial R&D, cell and gene therapy R&D, testing and production and other fields


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