Extraction and separation of palm leaf anti-hetamine and preparation of Yanhuso ethyl.

palmatine, also known as palmatine, and sulphate, also known as dltetrahydro palmatine sulphate.
corydalis B is a sedative used to relieve pain caused by diseases of the stomach system, progenitic pain, headaches, insomnia, etc.chinese medicine Yanhuso (Yuanhu, a block root of Corydalis yanhusuo W.T. Wang) contains very little Yanhuso ethyl, while its dehydrogenated
compound
bamatin is high in some plants. The roots of fibreursa recisa paerre, an anti-virus plant in southern China, contain Bamatin, which is then hydrogenated to prepare Yanhuso ethyl.Huang Fuji has been included in the "herb outline", Li Zhizhen referred to as "Fujisheng Lingnan, if the form of defense has been, but people often take this vine, even if the diet is poisonous, it is natural not to." Modern folk as a heat anti-inflammatory medicine. It is commonly used for trauma infection, tonsillitis, pharyngitis, conjunctivitis, hot ticks and jaundice.the purpose of the experiment:
1. Master a method of extraction of seasonal ammonium alkaloids.
2. To master the general chemical and chemical properties of alkaloids and their relationship between structure and properties.
3. To understand the relationship between the structure and properties of the alkaloids of the yellow vine.
4. Be familiar with the conditions and methods of alkaloid precipitation reaction.
5. Master the method and refining of alkaloid crystalline salts.
6. Master the preparation method of tyhydrobamatin.the chemical and chemical properties of known ingredients in yellow vines:the main component contained in the roots and roots of yellow vines is Bamatin. Still contains a small amount of medicinal root base, yellow vine armor, yellow vine ethyl, endolipid and sterols. It is also referred to as the inclusion of small pyridine in roots, roots and bark.
1.Palmatine (Palmatine)
This product is season ammonium alkaloid, soluble in water, ethanol, almost insoluble in chloroform, ether, benzene and other solvents, palm leaf anti-alkali hydrochloride (palmation Chloride) C21H22O4N . Cl.3H2O is a yellow needle crystallization with a melting point of 205 degrees C (decomposition). Its chemical and chemical properties are similar to that of small pyridine hydrochloric acid. Palmatine icdide C21H22O4N I.2H2O is orange-yellow needle crystallization with a melting point of 241 degrees C (decomposition).2. Drug root alkali (Yato alkali) Jatrorrhizine
is a phenolic hydroxytiamide salt with a chemical and chemical properties similar to Bamatin, but more soluble in the caustic lye, its hydrochloric acid in water is also more soluble than Bamatin hydrochloric acid, can be separated by this property. Jatrorrhizine Chloride C20H20O4N Cl. H2O is a copper-colored needle crystallization with a solution point of 204 to 206 degrees C and a bitter acid (Jatrorrizine picrate) C20H20O4N. C6H2O7N2 is an orange-yellow column crystallization with a solution point of 217 to 220 degrees C (decomposition).3. Small jaundium base (jaundium Berberine)
this product is seasonal ammonium alkaloid, its free alkali is yellow long needle crystallization, C20H18O4N. OH.5 H2O, solubility point 145 degrees C, at 100 degrees C
dry
, loss of crystalline water turned brown.
small pyridine can slowly dissolve in water (1:20), ethanol (1:100), more easily soluble in hot water, thermal ethanol, micro-soluble in acetone, chloroform, benzene, almost insoluble in petroleum ether, small pyridine and chloroform, acetone, benzene can form a compound. Berberine Chloride C20H16O4N Cl2H2O, melting point 205 degrees C (decomposition), slightly soluble in cold water, more easily soluble in boiling water, its nitrates and hydroiodates, extremely insoluble in water (cold water about 1:2000). The neutral sulfates, phosphates and acetates of the small pyridine are more soluble in the water, and the salts of the small pyridine are solubility in the water: .