F2 generation hybrid insect-resistant cotton can effectively reduce or even reverse the resistance of red bellworms.

Biotechnology Channel News: With the development and popularization of GM technology, the resistance of crop pests to GM crops has attracted more and more attention.
Chinese and American researchers reported in the new issue of the Proceedings of the National Academy of Sciences on the 8th, the use of genetically modified cotton and conventional cotton hybridization to grow a second generation of insect-resistant cotton, can effectively reduce or even reverse the resistance of red bellworms.
The Institute of Plant Protection of the Chinese Academy of Agricultural Sciences, in collaboration with the Hubei Academy of Agricultural Sciences and the University of Arizona, has conducted 11 years of research on the interaction between genetically modified Bt cotton and red bellworms in the Yangtze River basin of China, proving the effectiveness of this hybridization strategy.
Wu Kongming, author of the paper and a researcher at the Plant Conservation Institute, told Xinhua that the Yangtze River basin red bellworm had entered an early stage of resistance about 2008, but since then people have begun to grow large-scale F2 hybrid insect-resistant cotton.
This insect-resistant cotton father is mostly insect-resistant cotton line, the mother is mostly conventional cotton line, so the production of some ordinary cotton plants, these ordinary cotton for the red bellworm provides a shelter, effectively solve the problem of red bellworm resistance.
Wu Kongming explained that the resistance of red bellworms is mostly due to mutations in the Bt-subject calcium mutant protein gene, which is recessive.
After planting F2 generation hybrid insect-resistant cotton, the hybrids produced by the mating of the Bt cotton plant's surviving resistant redbell worm with the shelter-protected non-resistant redbell worm can still be killed by Bt cotton, thus preventing the formation of an resistant redbell population.
researchers further monitored the occurrence and Bt resistance level of 17 monitoring points in 6 provinces in the Yangtze River basin, and showed that with the large-scale production application of F2 generation hybrid insect-resistant cotton, the resistance development of redbell worm to Bt cotton was effectively controlled.
"This study proves for the first time that Bt crop and non-Bt crop seed mixing can effectively control pest resistance, and develops new methods and strategies for pest resistance management, which is of great theoretical and applied significance for promoting the development of environmental risk management of Bt crop industry and GENETIC crops," Wu said.
" transBt gene crop refers to the introduction of suyun gold spores gene crops.
, trans-Bt gene insect-resistant cotton, corn and soybeans have been widely planted around the world, effectively controlling the occurrence and harm of pests, significantly reducing the use of chemical pesticides.
, in recent years, cases of failure to control due to pest resistance have emerged and have become the most important factor affecting the sustainable use of Bt crops.
In order to delay the production of pest resistance, developed countries such as the United States often adopt a shelter strategy, i.e. planting a certain percentage of non-Bt crops near Bt crops as shelter for pests, so that the pest's adversary genes can be effectively diluted.
But it is difficult for farmers in developing countries to adhere strictly to this rule, in which India's red bellworms have become resistant to Bt cotton, and the advantage of F2 generation hybrid insect-resistant cotton is that there is no mandatory requirement for so-called shelters.
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