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Front Oncol: Comparison of survival results between laparoscopic and open radical hysterectomy for the 2018 edition of FIGO IA2-IIA2 cervical cancer patients: a weighted analysis of propensity scores

 Last Update: 2021-12-03
 Source: Internet
 Author: User

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Recently, Frontiers in Oncology published a research result by the research team of Shengjing Hospital affiliated to China Medical University , based on the 2018 International Federation of Obstetrics and Gynecology (FIGO) staging, relatively open ( ORH ) and laparoscopic radical hysterectomy surgery (LRH) treatment IA2-IIA2 survival and relapse result of cervical cancer
.

Based on the 2018 International Federation of Obstetrics and Gynecology (FIGO) staging, Shengjing Hospital Affiliated to China Medical University compares the survival and recurrence results of open ( ORH ) and laparoscopic radical hysterectomy (LRH) for the treatment of stage IA2-IIA2 cervical cancer .

Retrospective analysis of 2013 Nian 1 Yue 1 - The 2016 Nian 12 Yue 31 in Shengjing Hospital of China Medical University, underwent open or laparoscopic radical hysterectomy in May 1373 cases of early cervical cancer data
.

Propensity score-based processing weighted inverse probability (PS-IPTW) was used to balance the covariates between the two groups

2013 Nian 1 Yue 1 to 2016 Nian 1 Yue 1 , a total screening of 1373 patients with early cervical cancer

The median follow-up time in the ORH group was 61 months ( range 23-94 months ) , while the median follow-up time in the LRH group was 57.

Prognostic analysis of two treatment methods in FIGO staging of 2009 edition

The prognostic analysis of the 2009 edition of FIGO staging and two treatment methods Prognosis analysis of the 2009 edition of FIGO staging and two treatment methods

After re-staging according to the 2018 FIGO staging standard, IPTW adjusted the OS (Log-Rank P = 0.
143) and PFS (Log-Rank P = 0.
137) of the first two treatments without significant difference
.

The 5-year PFS rates of ORH group and LRH group were 88.

After re-staging according to the 2018 FIGO staging standard, IPTW adjusted the OS (Log-Rank P = 0.

Prognostic analysis of two treatment methods in FIGO staging of 2018 edition

2018 version of FIGO staging and two treatment methods prognostic analysis 2018 version of FIGO staging and two treatment methods prognostic analysis 2018 version ofFIGO staging and two treatment methods prognostic analysis

2018 Edition FIGO criteria IIIC1p-IIIC2p patients in stage, ORH group died 26 is cases of LRH group died .
6 patients 5 years OS rates were 78.
6% and 72.
2% (the Log-Rank P = 0.
579)
.

ORH group 27 recurrences of LRH group .

2018 Edition FIGO criteria IIIC1p-IIIC2p patients in stage, ORH group died 26 is cases of LRH group died .

Before adjustment, grouping, age, tumor size, LVSI and parauterine invasion were confirmed to be related to the survival status of cervical cancer patients

In summary, this retrospective study shows that the efficacy of ORH in the treatment of patients with stage IA2-IIA2 cervical cancer is in line with the NCCN guidelines, but some patients without adverse prognostic factors using LRH treatment are not inferior to ORH
.

This retrospective study showed that the efficacy of ORH in the treatment of patients with stage IA2-IIA2 cervical cancer is in line with the NCCN guidelines, but some patients without adverse prognostic factors using LRH treatment are not inferior to ORH

Original source:

Zhao W, Xiao Y, Zhao W, Yang Q and Bi F (2021) Survival Outcomes in Patients With 2018 FIGO Stage IA2--IIA2 Cervical Cancer Treated With Laparoscopic Versus Open Radical Hysterectomy: A Propensity Score-Weighting Analysis.

Front.
Oncol.
11 :682849.
doi: 10.
3389/fonc.
2021.
682849

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